Re:[NMusers] Diagnostics for multiple analytes in Xpose4

2011-09-14 Thread wangxipei
Dear Hussain, I think you can get the individual diagnostic plots by setting some arguments in Xpose4: e.g. basic.gof(xpose.data(run-number),by="CMT",layout=c(2,1)) basic.gof(xpose.data(run-number),subset="CMT==2",layout=c(2,1)) Best regards, Xipei -- Xipei Wang, Ph.D. student Department

Re:Re: [NMusers] Parent and metabolite model-residual error model and L2

2011-09-03 Thread wangxipei
of the observations at TIME=112.5. > >ID TIME AMT APGR WT DV TYPE L2 >1 0. 25.0 1.4 7 . . 1 >1 2.0 . 1.4 7 6.0 1 1 >1 2.0 . 1.4 7 17.3 2 1 >1 12.5 3.5 1.4 7 . 2 2 >1 24.5 3.5 1.4 7 . 2 2 >1 37.0 3.5 1.4 7 . 2 2 >1 48.0 3.5 1.4 7 . 2 2 >1 60.5 3.5 1.4 7 . 2 2 >1 72.5

Re:[NMusers] Parent and metabolite model-residual error model and L2

2011-09-02 Thread wangxipei
Center, Beijing, China Email: wangxi...@gmail.com At 2011-09-02 14:31:43,wangxipei wrote: Dear NONMEM users, I am building a popPK model for a parent drug and its metabolite (rich data,single dose). I want to estimate the correlation between the residual errors of parent drug and its metabolite

[NMusers] Parent and metabolite model-residual error model and L2

2011-09-01 Thread wangxipei
Dear NONMEM users, I am building a popPK model for a parent drug and its metabolite (rich data,single dose). I want to estimate the correlation between the residual errors of parent drug and its metabolite, because their measurements were from a same blood sample. (My code and part of data are

[NMusers] NONMEM codes about PK analysis from a cross-over study design

2011-03-15 Thread wangxipei
Dear NONMEM users, I have a data set from a bioavailablity study (2×2 study design). 18 people took a single dose of a marketed drug (marked as R), then after a wash-out period, took a single dose the corresponding generic drug (marked T). I want to estimate the PK parameters of T and R sep