Behalf Of ishida...@chugai-pharm.co.jp
Sent: Wednesday, March 16, 2011 3:19 PM
To: wangxi...@gmail.com; nmusers@globomaxnm.com
Subject: RE: [NMusers] NONMEM codes about PK analysis from a cross-over
study design
Dear Xipei
I recommend you use EVID=4 at time=0 in the 2nd period on the dataset
(6)*EXP(ETA(6))
F1=THETA(7) *EXP(ETA(7)); Relative BA parameter
ENDIF
Thanks!
Yoshi
From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On
Behalf Of wangxipei
Sent: Wednesday, March 16, 2011 2:51 PM
To: nmusers
Subject: [NMusers] NONMEM codes about PK analysis from
Dear NONMEM users,
I have a data set from a bioavailablity study (2×2 study design). 18
people took a single dose of a marketed drug (marked as R), then after a
wash-out period, took a single dose the corresponding generic drug (marked T).
I want to estimate the PK parameters of T and R sep
