From: Ethan Wu [mailto:ethan.w...@yahoo.com]
Sent: Friday, September 17, 2010 9:13 AM
To: Bauer, Robert; nmusers@globomaxnm.com
Subject: Re: [NMusers] quality of SE estimate by IMP method
Hi Bob,
IMP/MAP also came back with pretty similar OBJ like IMP.
Below is the
Bauer, Robert"
To: Ethan Wu ; nmusers@globomaxnm.com
Sent: Thu, September 16, 2010 2:26:07 PM
Subject: RE: [NMusers] quality of SE estimate by IMP method
Yes. Read the METHOD=CHAIN section in the intro712.pdf manual.
Robert J. Bauer, Ph.D.
Vice President, Pharmacometrics
ICON Development
From: Ethan Wu [mailto:ethan.w...@yahoo.com]
Sent: Thursday, September 16, 2010 12:19 PM
To: Bauer, Robert; nmusers@globomaxnm.com
Subject: Re: [NMusers] quality of SE estimate by IMP method
Hi Bob,
Is there a way to pick up from the last run with SAEM/IMP so to only
run the additional step
robert.ba...@iconplc.com
Web: www.icondevsolutions.com
From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On
Behalf Of Ethan Wu
Sent: Thursday, September 16, 2010 11:46 AM
To: nmusers@globomaxnm.com
Subject: [NMusers] quality of SE estim
: www.icondevsolutions.com
From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com]
On Behalf Of Ethan Wu
Sent: Thursday, September 16, 2010 11:46 AM
To: nmusers@globomaxnm.com
Subject: [NMusers] quality of SE estimate by IMP method
Dear uses,
I
Dear uses,
I am using NM7 SAEM method for an analysis. As I learned from NM7 workshop, I
used IMP method after SAEM to generate SE estimate.
In this case, at the end of SAEM iteration, OBJ was quite stable and negative
several thousand.
But, with IMP, after 5 iterations, Obj was up to posit