RE: [NMusers] quality of SE estimate by IMP method

2010-09-17 Thread Bauer, Robert
From: Ethan Wu [mailto:ethan.w...@yahoo.com] Sent: Friday, September 17, 2010 9:13 AM To: Bauer, Robert; nmusers@globomaxnm.com Subject: Re: [NMusers] quality of SE estimate by IMP method Hi Bob, IMP/MAP also came back with pretty similar OBJ like IMP. Below is the

Re: [NMusers] quality of SE estimate by IMP method

2010-09-17 Thread Ethan Wu
Bauer, Robert" To: Ethan Wu ; nmusers@globomaxnm.com Sent: Thu, September 16, 2010 2:26:07 PM Subject: RE: [NMusers] quality of SE estimate by IMP method Yes.  Read the METHOD=CHAIN section in the intro712.pdf manual. Robert J. Bauer, Ph.D. Vice President, Pharmacometrics ICON Development

RE: [NMusers] quality of SE estimate by IMP method

2010-09-16 Thread Bauer, Robert
From: Ethan Wu [mailto:ethan.w...@yahoo.com] Sent: Thursday, September 16, 2010 12:19 PM To: Bauer, Robert; nmusers@globomaxnm.com Subject: Re: [NMusers] quality of SE estimate by IMP method Hi Bob, Is there a way to pick up from the last run with SAEM/IMP so to only run the additional step

Re: [NMusers] quality of SE estimate by IMP method

2010-09-16 Thread Ethan Wu
robert.ba...@iconplc.com Web: www.icondevsolutions.com     From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of Ethan Wu Sent: Thursday, September 16, 2010 11:46 AM To: nmusers@globomaxnm.com Subject: [NMusers] quality of SE estim

RE: [NMusers] quality of SE estimate by IMP method

2010-09-16 Thread Bauer, Robert
: www.icondevsolutions.com From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of Ethan Wu Sent: Thursday, September 16, 2010 11:46 AM To: nmusers@globomaxnm.com Subject: [NMusers] quality of SE estimate by IMP method Dear uses, I

[NMusers] quality of SE estimate by IMP method

2010-09-16 Thread Ethan Wu
Dear uses,   I am using NM7 SAEM method for an analysis. As I learned from NM7 workshop, I used IMP method after SAEM to generate SE estimate.   In this case, at the end of SAEM iteration, OBJ was quite stable and negative several thousand.   But, with IMP, after 5 iterations, Obj was up to posit