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-Original Message-
From: owner-nmus...@globomaxnm.com On Behalf Of
Leonid Gibiansky
Sent: Friday, January 26, 2024 7:42 AM
To: Jeroen Elassaiss-Schaap (PD-value B.V.) ; Elashkar,
Omar I. ; nmusers@globomaxnm.com
Subject: Re: [NMusers] NONMEM Error on SAEM but not FOCEI
CAUTION: This
Depends. I have come across cases with large variances where you get an
overflow to zero in SAEM. It is however not very likely with a
closed-form PK model.
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On 26-01-2024 16:41, Leonid Gibiansky wr
Dear Omar,
What you describe is not that strange. It can happen because SAEM does
random sampling whereas FOCE-I uses a directed search. Therefore extreme
values can occur with SAEM. Please refer to the section I60 of user
guide for v7+ "Stable Routines for Estimation Methods and AutomatedÂ
type = "typo", something similar is in the control stream where Q is
defined
Leonid
On 1/26/2024 10:16 AM, Leonid Gibiansky wrote:
most likely, some type in the code. Can you provide the control stream?
On 1/26/2024 10:01 AM, Elashkar, Omar I. wrote:
ERROR IN TRANS4 ROUTINE
most likely, some type in the code. Can you provide the control stream?
On 1/26/2024 10:01 AM, Elashkar, Omar I. wrote:
ERROR IN TRANS4 ROUTINE
