;
nmusers@globomaxnm.com
Subject: Re: [NMusers] RE: Link different thetas to same omega using mu
referencing
Hi Jacob,
Yes, THETA(4) would represent the typical value (before exponentiation). In
summary, writing your covariate code after the definition of MU should
circumvent the time-varyi
;
; "'Sadler, Brian'" ;
"nmusers@globomaxnm.com"
Sent: Wednesday, April 13, 2016 2:00 PM
Subject: RE: [NMusers] RE: Link different thetas to same omega using mu
referencing
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om
Sent: Wednesday, April 13, 2016 11:44 AM
Subject: RE: [NMusers] RE: Link different thetas to same omega using mu
referencing
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: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On
Behalf Of Rupert Austin
Sent: Wednesday, April 13, 2016 11:44 AM
To: 'Sadler, Brian'; nmusers@globomaxnm.com
Subject: RE: [NMusers] RE: Link different thetas to same omega using mu
referencing
I’m not sure th
I’m not sure that Brian’s suggestion is acceptable due to the following
constraint I quote from one of the NONMEM manuals:
“Time dependent covariates cannot be part of the MU_ equation”
If CAT is time-varying (as suggested by Jacob) then “MU_1 = CAT1*THETA(1) +
CAT2*THETA(2) + CAT3*THETA(