Penelitian begini biasanya dilakukan oleh orang kafir...
Islam itu artinya, sekarang ini, kemacetaan dan kedunguan serta
kebiadaban dan kebuasan.
Agar jelas: Islam itu adalah laknatullah...
BBC NEWS
Self-repair gene therapy promise
Gene therapy experts say they have found a way to persuade cells to
repair themselves.
Instead of replacing a faulty gene, the new approach harnesses the
cells' own correctional mechanisms.
German researchers showed a drug could influence the way a gene
behaved in patients with a debilitating genetic condition.
Details of the research are being presented to the European Society of
Human Genetics conference in Amsterdam.
This work shows that it may be possible to stimulate a
related gene, and reduce the symptoms of the disease
Dr Fred Kavalier, British Society of Human Genetics
The research focussed on spinal muscular atrophy (SMA), a relatively
common inherited disease, and the leading cause of death in infants,
affecting about one in every 6,000 newborns.
Due to degeneration of the motor neurons in the spinal cord patients
develop muscle weakness and atrophy of the legs, arms and trunk.
In patients with SMA the survival motor neuron gene (SMN1) is
deleted, but they all carry a copy gene (SMN2).
However, this only produces about 10% of the correct protein which is
insufficient to prevent the diseases.
The severity of the SMA is influenced by the number of SMN2 genes,
which normally vary between one and four - the more copies there are
the better the patient fares.
Protein levels boost
The researchers, from the Institute of Genetics at the University of
Cologne investigated a drug called valproate, which is already used to
treat epilepsy.
Lab tests had shown it could increase levels of the SMN protein by up
to four times.
Valproate was also found to raise SMN levels in brain tissue.
The team first treated 10 parents of children with SMA with valproate
for four months.
It was found that using the drug significantly increased SMN levels in
blood.
Following this, 20 SMA patients were treated with valproate.
Seven showed increased SMN2 levels in their blood.
'A small step'
However, it remains unclear whether SMN expression in blood reflects
SMN expression in motor neurons, and would therefore have an effect on
muscle strength.
But the researchers said they hoped their findings could have
significant benefits in the future.
Professor Brunhilde Wirth said: "The long-term outcome could be both
improved therapy to enable a better quality of life for SMA patients,
and also the introduction of neonatal screening so that therapy could
be started before the first symptoms appear."
Dr Fred Kavalier, of the British Society of Human Genetics,
said: "This work shows that it may be possible to influence the
behaviour of genes with drugs.
"This is not a cure for SMA, but it's a small step along the road that
may lead to an effective treatment.
"It is exciting to discover that a drug that is used to treat
epilepsy may also be helpful in a completely different condition."
Professor Robin Lovell-Badge, head of genetics at the Medical
Research Council's National Institute for Medical Research, said it
was crucial to obtain detailed basic understanding of specific genes,
and the nature of the defects responsible for genetic disease before
the knowledge was applied to treating patients.
He added: "It is still too early to say whether or how well these
particular approaches will work in the clinic,.
"But the preliminary results are encouraging and the knowledge gained
will hopefully generate yet further tricks to bypass the unlucky set
of cards that some people are dealt."
Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/4976984.stm
Published: 2006/05/07 23:10:23 GMT
© BBC MMVI
------------------------ Yahoo! Groups Sponsor --------------------~-->
Protect your PC from spy ware with award winning anti spy technology. It's free.
http://us.click.yahoo.com/97bhrC/LGxNAA/yQLSAA/uTGrlB/TM
--------------------------------------------------------------------~->
Post message: [EMAIL PROTECTED]
Subscribe : [EMAIL PROTECTED]
Unsubscribe : [EMAIL PROTECTED]
List owner : [EMAIL PROTECTED]
Homepage : http://proletar.8m.com/
Yahoo! Groups Links
<*> To visit your group on the web, go to:
http://groups.yahoo.com/group/proletar/
<*> To unsubscribe from this group, send an email to:
[EMAIL PROTECTED]
<*> Your use of Yahoo! Groups is subject to:
http://docs.yahoo.com/info/terms/
