Hi Michael, All,

In both the cases, i.e., google doc vs directly working on the source/note 
(HTML), we would need following to start (as this group is with very 
multidisciplinary experts) and move ahead:

1.       First agree on a structure (i.e., TOC) for each note

2.       Assigning sections to respective experts

3.       Merge the sections/contents

4.       Take feedback/comments on a first complete draft

5.       Finalise the note

Regards,
Ratnesh

From: Michael Miller [mailto:michael.mil...@systemsbiology.org]
Sent: Friday, April 1, 2016 5:04 AM
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Subject: RE: PDDI Info Task Force (Standard sub-group) - Minutes/recording for 
3/31

hi all,


Rich proposed that a process for writing whereby we select certain sections to 
focus on and develop content using google docs. Rich and the other editors will 
migrate the content into the W3C note format

No objection was raised
this can work, if we anticipate that a lot of people will be working on the 
same section simultaneously.  but in other groups, i've seen one person 
assigned to write the first draft, submit a pull request that people then 
comment on and once people are happy with the updates it's merged.  that way 
the process is captured by the source control.  people working on different 
sections won't collide in the merges.

cheers,
michael

Michael Miller
Software Engineer
Institute for Systems Biology



From: Richard Boyce [mailto:rd...@pitt.edu<mailto:rd...@pitt.edu>]
Sent: Thursday, March 31, 2016 1:26 PM
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cjvit...@partners.org<mailto:cjvit...@partners.org>; 
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Subject: PDDI Info Task Force (Standard sub-group) - Minutes/recording for 3/31

(FYI for those on public-semweb-lifesci who are not participating....)

Dear Colleagues,

Below are pasted the minutes of the Standard sub-group for the PDDI DDI Minimum 
Information Model Task Force [1]. Please note that the next meetings scheduled 
in April are as follows:

- Standard development sub-team:
    April 29th (Friday) at 1-2 Eastern

-  Content sub-team:
    April 29th (Friday) at 3-4 Eastern

Please expect me to send out 2 doodle polls within the next week or so to 
obtain new meeting times for 1) an all team call in May to summarize progress 
and discuss the medication reconciliation use case, and 2) sub-team meetings 
for the May - July.

1. https://sites.google.com/site/ddikrandir/home/ddi_info_model_taskforce
Minutes for 3/31/2016 (Standard subgroup)


In Attendance : Chris Vitale (PHS), Daniela & Ratnesh, Kim Nolen, Laura 
Slaughter, Maria Herrero, Mathias Brochhausen, Matthias Thomas Samwald, Richard 
Boyce, Schneider, Jodi, Xia Jing


Meeting recording: http://goo.gl/yx4nn7


Meeting:

Update from the Content subteam

Selected PDDIs and plans for the next couple of months

Noted especially 1) PDDIs will be selected to represent boundary cases for each 
of the information categories, and 2) the content sub-team plans to develop 
decision trees for all of the chosen PDDIs (~20)

Toward writing an Interest Group Note

Ratnesh proposed an outline for the interest note where there would actually be 
multiple notes - one as an introduction and background with stakeholder 
descriptions, use cases, and user scenarios; and then one each for evidence 
reporting, the information model, and links to ontologies and terminologies

No objection was raised to this idea

An github project and initial draft:

GitHub project: https://github.com/W3C-HCLS/w3c-ddi

Example draft : http://goo.gl/7ZaE94

Rich proposed that a process for writing whereby we select certain sections to 
focus on and develop content using google docs. Rich and the other editors will 
migrate the content into the W3C note format

No objection was raised


Progress on definitions

Discussion of stakeholders

The question of who the stakeholders are for the min info model came up from 
the Standard sub-team. Rich presented of stakeholders suggested by the content 
sub-team which was expanded during the call to the following:

Clinicians (doctors, nurses, pharmacists, and various practitioners) who must 
use PDDI information to make clinical decisions

Persons who create systems that provide PDDI information to clinicians in 
various settings (e.g., database vendors, persons who have PDDI knowledge and 
want to represent it, drug information editorial boards)

Organizations that provide publicly available lists of drug-drug interactions 
(e.g., developers of RxNorm)

Clinical researchers who can generate evidence about PDDIs (e.g, translational 
research on PDDIs)

Academics / researchers who want to use the PDDI data in various research 
projects ranging from data mining to information retrieval to clinical research 
(evidence generation - more towards perhaps pharmacovigilance)

Pharmaceutical company, contract research organization - e.g. during pre-market 
studies (e.g., clinical trials) to guide medication safety during premarket 
research

Patient (maybe) -- receiving end of a clinical encounter where the clinician 
provides information provided by this model

Patient (maybe) -- searching for information

TODO: Rich will pull this into a google doc in the format of user profile and 
scenarios for discussion by the sub-team with the goal of finalizing by the 
next call

Knowledge representation goal for the model

to what degree should it support inference?

Rich used the Warfarin and NSAIDs PDDI to discuss how how “semantically rich” 
(and rigid) the data model will be. The discussion was aided by a draft list of 
theses developed by Mathias B.

The ‘straw man’ proposal is that the ~7 information categories we are focusing 
on should be “semantically rich” (i.e., logically consistent formal 
definitions, realist orientation, upper ontology)

I.e., treat the six core terms and all terms/concepts that get related to those 
as information entities

Then, integrate or use multiple commonly used data schemata, terminologies and 
ontologies to provide the terms, data elements, and representations that are 
then linked to our ~7 core terms.

TODO: Rich will put the draft list of theses into a google doc and share with 
the sub-team to arrive at a final set of desiderata to guide future development.

We went over the spreadsheet discussing proposed definitions

Lots of good proposals and discussion.

One proposal was to split “frequency of harm and exposure” into two categories

No objects so we will proceed that way

This will be organized over the next couple of weeks so we can refine and move 
toward a final recommendation for each

Rich will likely create a google doc or sheet for each category to organize and 
summarize the discussion

Next steps

Look for doodles to schedule new meetings after April

Work on user scenario and standard desiderata google docs when sent out

Work toward finalizing definition for “clinical consequences” when a doc or 
sheet sent out

Plan to work out a process to get the other definitions done at our next meeting


Kind regards!
-Rich

--

Richard D Boyce, PhD

Assistant Professor of Biomedical Informatics

Faculty, Center for Pharmaceutical Policy and Prescribing

Faculty, Geriatric Pharmaceutical Outcomes and Gero-Informatics Research and 
Training Program

University of Pittsburgh

rd...@pitt.edu<mailto:rd...@pitt.edu>

Office: 412-648-9219

Twitter: @bhaapgh

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