On 07/06/2012 11:10 AM, Lin MD, Simon wrote:
It would be interesting to see a link from the drugs to genes for DNA
testing on the FDA label:
http://www.fda.gov/Drugs/ScienceResearch/ResearchAreas/Pharmacogenetics/ucm083378.htm
This interest has been expressed by some of my colleagues here at Pitt
as well. Looking at the webpage, it looks like the drug column uses UNII
preferred terms and the label sections use standard syntax. Not sure
what is used for the string names in the biomarker and therapeutic area
columns but they look easy to map - can someone hazard a guess? Once we
know that, I could script a database table from the html table of
ucm083378.htm and create mappings to the referenced sections in
LinkedSPL for drug products containing the active moieties listed in the
Drug column. Would interested folks please provide a use case that I
will use along with the use case for my colleagues to make the mapping
immediately useful?
best,
-Rich
Best regards,
Simon
==================================================
Simon Lin, MD
Director, Biomedical Informatics Research Center
Marshfield Clinic Research Foundation
1000 N Oak Ave, Marshfield, WI 54449
Office 715-221-7299
lin.si...@mcrf.mfldclin.edu
www.marshfieldclinic.org/birc
For scheduling assistance, please contact
Crystal Gumz, Administrative Secretary
gumz.crys...@mcrf.mfldclin.edu
715-221-6403
*From:*Richard Boyce [mailto:rd...@pitt.edu]
*Sent:* Friday, July 06, 2012 9:41 AM
*To:* public-semweb-lifesci@w3.org
*Subject:* FYI: rxnorm mappings in LinkedSPLs
FYI - for those interested in a linked version of US drug product
labeling, I added mappings to RxNORM for active moieties and drug
products in the FDA product label data served by LinkedSPLs
(http://tinyurl.com/7hyd44g). The mappings go to the Purls served by
the Bioportal SPARQL endpoint. Active moieties are mapped using the
dailymed:activeMoietyRxCUI property while product mappings use
dc:subject. Importantly, SPLs for products containing multiple active
moieties (e.g., http://tinyurl.com/78hu8l3) and multiple dose forms
(e.g., http://tinyurl.com/7987rjh) seem to be handled correctly. I
plan to add drug class mappings w/in the next two weeks. Feedback and
suggestions are quite welcome.
kind regards,
-Rich Boyce
--
Richard Boyce, PhD
Assistant Professor of Biomedical Informatics
Faculty, Geriatric Pharmaceutical Outcomes and Gero-Informatics Research and
Training Program
Scholar, Comparative Effectiveness Research Program
University of Pittsburgh
rd...@pitt.edu <mailto:rd...@pitt.edu>
412-648-9219 (W), 206-371-6186 (C)
Twitter: @bhaapgh
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Richard Boyce, PhD
Assistant Professor of Biomedical Informatics
Faculty, Geriatric Pharmaceutical Outcomes and Gero-Informatics Research and
Training Program
Scholar, Comparative Effectiveness Research Program
University of Pittsburgh
rd...@pitt.edu
412-648-9219 (W), 206-371-6186 (C)
Twitter: @bhaapgh
