"Introduction to computing and programming with Python: A Multimedia Approach" by Mark Guzdial, a CS professor at Georgia Tech.
It uses the Jython Environment for Students (JES). You can use this to for example work with and manipulate images or sounds.
A similar book is available in preview form: "Introduction to Media Computation: A Multimedia Cookbook in Python".
See this page for info on the books, the software, course notes, research papers, and more info: http://coweb.cc.gatech.edu/mediaComp-plan
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