I just noticed that pywin32 does not work with vista directly (tried import win32clipboard, => ImportError). The problem is the installer name; it's the usual
pywin32-210-win32-py2.5.exe It needs to be renamed to: pywin32-210.win32-setup-py2.5.exe In order for vista to catch it as "installer". We renamed the IPython exe installer to have "setup" to get around the same issue. Just posting this for benefit of googlers. I'll complain about this on distutils-sig as well. -- http://mail.python.org/mailman/listinfo/python-list