I beg your pardon if this is too off topic. I am posting here
since I hope to find an R solution to my problem. Please indulge
me while I give a little background about what I'm trying to do.
I'm on a DSMB for a clinical trial. The Steering Committee for the
trial has asked us to perform a futi
What does this particular Steering Committee think a "futility
analysis" is? Do they have any particular reference(s)? What do you
find in your own literature review?
If it were my problem, I think I'd start with questions like that.
Your comments suggested to me a confoun
Steve.
> -Original Message-
> From: [EMAIL PROTECTED] [mailto:r-help-
> [EMAIL PROTECTED] On Behalf Of Spencer Graves
> Sent: 22 February 2006 03:45
> To: Kevin E. Thorpe
> Cc: R Help Mailing List
> Subject: Re: [R] OT Futility Analysis
>
> What does th
Thank you Spencer and Steve for your helpful comments. If I may, I
would like to elaborate on some of the points you raise.
Stephen A Roberts wrote:
> I would take the line that if they hadn't pre-specified any stopping
> rules, the only reason to stop is safety or new external data. I
> would be
On Wed, 2006-02-22 at 11:57 -0500, Kevin E. Thorpe wrote:
> Thank you Spencer and Steve for your helpful comments. If I may, I
> would like to elaborate on some of the points you raise.
Kevin,
I am not sure if you received any offlist replies to your post. Given
the subject matter, I had conside