[scikit-learn] Would love to contribute to this library that I fell in love with. I have a question! FIRST TIMER

2018-07-16 Thread Abhishek Babuji
TO WHOM IT MAY CONCERN, I have just learned Python to a level that I can say I'm comfortable with it. I have also picked up and learned Git and GitHub, and so now I'm ready to make my contribution to this library. I'm really enthusiastic but since this is my first time, I'd like to know a few thi

Re: [scikit-learn] sample_weights in RandomForestRegressor

2018-07-16 Thread Brown J.B. via scikit-learn
Dear Thomas, Your strategy for model development is built on the assumption that the SAR (structure-activity relationship) is a continuous manifold constructed for your compound descriptors. However, SARs for many proteins in drug discovery or chemical biology are not continuous (consider kinase i