Hello,

The version of msconvert that is shipped with TPP is a couple of years old
and does not know about that instrument.  You have three options to convert
your files:

1. Download and install a newer version of ProteoWizard, run the
conversion, and use that mzML file in Comet.  This is likely the simplest
and most expedient.

2. Use the command-line to convert the file, using the
--ignoreUnknownInstrumentError flag, for example:
  msconvert.exe --ignoreUnknownInstrumentError
c:\TPP\data\TMT_Microbiome\Xu_20210512_IRIstudy_Concentration_TMT_Plate1_D.raw


3. We will be releasing a new version of TPP later this week.  If you are
able to wait, then just update to the new version, which includes a more
recent version of msconvert.   This is recommended as long as you can wait
a few days to process your data.

Hope this helps,
--Luis


On Mon, Feb 13, 2023 at 8:32 AM Aarthie Senathirajah <
animallover....@gmail.com> wrote:

> Hi I'm currently trying to analyze the raw files from this metaproteomic
> dataset of the human gut microbiome. Which uses maxquant usually but i
> would like to use Comet.
> Firstly I am getting this error when trying to convert the raw file into
> mzml
> processing file:
> c:/TPP/data/TMT_Microbiome\Xu_20210512_IRIstudy_Concentration_TMT_Plate1_D.raw
> [Reader_Thermo::fillInMetadata] unable to parse instrument model; please
> report this error to the ProteoWizard developers with this information:
> model(Orbitrap Exploris 480) name(Orbitrap Exploris Slot #162); if want to
> convert the file anyway, use the ignoreUnknownInstrumentError flag
>
>
> Which I'm not sure how to solve.. Any help would be great!
>
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