Public bug reported:

The "mafft" program hangs waiting for "disttbfast" to exit, but in some
cases "disttbfast" does not exit after many days. This problem only
seems to occur with a particular alignment of virus sequences:

/usr/bin/mafft --inputorder --adjustdirection --thread 4 --auto
phygo.Spbetalikevirus.backbone.seqs

ProblemType: Bug
DistroRelease: Ubuntu 20.04
Package: mafft 7.453-1
ProcVersionSignature: Ubuntu 5.4.0-45.49-generic 5.4.55
Uname: Linux 5.4.0-45-generic x86_64
NonfreeKernelModules: zfs zunicode zavl icp zcommon znvpair nvidia_modeset 
nvidia
ApportVersion: 2.20.11-0ubuntu27.8
Architecture: amd64
CasperMD5CheckResult: skip
Date: Mon Sep 28 13:28:52 2020
InstallationDate: Installed on 2020-06-15 (104 days ago)
InstallationMedia: Ubuntu-MATE 20.04 LTS "Focal Fossa" - Release amd64 
(20200423)
SourcePackage: mafft
UpgradeStatus: No upgrade log present (probably fresh install)

** Affects: mafft (Ubuntu)
     Importance: Undecided
         Status: New


** Tags: amd64 apport-bug focal

** Attachment added: "Problem viral sequences"
   
https://bugs.launchpad.net/bugs/1897559/+attachment/5414923/+files/phygo.Spbetalikevirus.backbone.seqs

** Description changed:

- The "mafft" program hangs waiting for "disttb" to exit, but in some
- cases "disttb does not exit after many days. This problem only seems to
- occur with a particular alignment of virus sequences:
+ The "mafft" program hangs waiting for "disttbfast" to exit, but in some
+ cases "disttbfast" does not exit after many days. This problem only
+ seems to occur with a particular alignment of virus sequences:
  
  /usr/bin/mafft --inputorder --adjustdirection --thread 4 --auto
  phygo.Spbetalikevirus.backbone.seqs
  
  ProblemType: Bug
  DistroRelease: Ubuntu 20.04
  Package: mafft 7.453-1
  ProcVersionSignature: Ubuntu 5.4.0-45.49-generic 5.4.55
  Uname: Linux 5.4.0-45-generic x86_64
  NonfreeKernelModules: zfs zunicode zavl icp zcommon znvpair nvidia_modeset 
nvidia
  ApportVersion: 2.20.11-0ubuntu27.8
  Architecture: amd64
  CasperMD5CheckResult: skip
  Date: Mon Sep 28 13:28:52 2020
  InstallationDate: Installed on 2020-06-15 (104 days ago)
  InstallationMedia: Ubuntu-MATE 20.04 LTS "Focal Fossa" - Release amd64 
(20200423)
  SourcePackage: mafft
  UpgradeStatus: No upgrade log present (probably fresh install)

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https://bugs.launchpad.net/bugs/1897559

Title:
  mafft hangs at 100% CPU for over a week

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