This is an important question Ann.  The research literature has focused on 
measuring traditional parameters in sepsis resuscitation, despite evidence 
these parameters suffer from failing to adequately reflect volume status and 
are often slow to change (CVP being one of the worst offenders).  More accurate 
assessments with ultrasound, both flow and image, are able to give a better 
idea of adequacy of resuscitation.  Measures such as stroke volume response and 
echo images of EF are likely, in my opinion, to replace most current measures 
that are used to guide resuscitation.  These parameters just need to be better 
studied in sepsis.  Their value in the perioperative and trauma settings, 
particularly stroke volume optimization, are well supported in research.  
Tom

Tom Ahrens PhD RN FAAN



-----Original Message-----
From: George Kramer <[email protected]>
To: Mulligan, Ann W. <[email protected]>
Cc: Sepsis list group ([email protected]) 
<[email protected]>
Sent: Mon, Aug 20, 2012 8:39 am
Subject: Re: [Sepsis Groups] Heart failure patients presenting with sepsis


Ann,


important question. I am just an observer of sepsis care, but this always seems 
to be a discussion with uncertain resolution.  often leading to delays in 
therapy.


ultrasound assessment of filling and contraction - diastolic and systolic 
function, would likely help decide when to give fluid to CHF patients as well 
as those with other co-morbidities or even most septic patients after 
substantial fluid.  When should drugs be administered and when should fluid be 
continued. etc.


Can echo be performed by an attending ICU doc, resident, nurse or does this 
require a cardiology consult?


g








George C Kramer, PhD

Director, Resuscitation Research Lab
Professor, Dept. of Anesthesiology
301 University Blvd.
UTMB, Galveston, TX 77555-1102








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email: [email protected]
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On Aug 17, 2012, at 12:13 PM, Mulligan, Ann W. wrote:



Our hospital continues to struggle withmeeting the fluid bolus requirements 
when a CHF patient with a low EF presentswith sepsis.  Cardiology is suggesting 
that ED perform a bedside ECHO ifthe patient has CHF and/or know reduced 
ejection fraction, and to be prudentwhen giving several liters of fluid.
 
How are other hospitals approaching thesepatients, and what is the latest 
guidelines for sepsis treatment within thisdiagnosis?

Ann Mulligan, RN, BSN, CPHQ 
 Manager  Quality & Outcomes 
 Alta Bates Summit Medical Center 
2450 Ashby Ave.
Berkeley, CA  94705
Ph: (510)204-2986
Fax: (510)204-1221
Cell: (510)325-4044 
[email protected] 
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and may contain material that is confidential and protected by stateand federal 
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