Answer: When you are producing clinically problematic worsening of oxygenation 
status (or rarely clinically significant worsening of unvented IACS).

With that much crystalloid you should also be considering adding albumin.
From: [email protected] 
[mailto:[email protected]] On Behalf Of Ahmed Mohamed 
Mukhtar
Sent: Friday, January 25, 2013 10:22 AM
To: [email protected]
Subject: [Sepsis Groups] maximal volume in severe sepsis and septic shock

Hi All
I read the new guideline of surviving sepsis campaign and it stated that ' 
Initial fluid challenge in patients with sepsis-induced tissue hypoperfusion 
with suspicion of hypovolemia to achieve a MINIMUM of 30 mL/kg of crystalloids' 
My question is what is the maximum fluid therapy during early resuscitation. In 
our hospital we put  60 mL/kg as the maximum volume of fluid resuscitation. Is 
there any published guidelines about the maximum volume resuscitation in septic 
shock
Regards
Ahmed Mukhtar
On Fri, Jan 25, 2013 at 4:58 PM, 
<[email protected]<mailto:[email protected]>>
 wrote:
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Today's Topics:

   1. Repeat Blood Cultures (Stotts, James)
   2. Sepsis Screening in Oncology and Transplant Patients
      (Stotts, James)
   3. survivor resources (Maurene Harvey)
   4. New Sepsis Guideline (seyed mohammad reza hashemian)


----------------------------------------------------------------------

Message: 1
Date: Thu, 24 Jan 2013 22:05:55 +0000
From: "Stotts, James" <[email protected]<mailto:[email protected]>>
To: 
"[email protected]<mailto:[email protected]>"
        
<[email protected]<mailto:[email protected]>>
Subject: [Sepsis Groups] Repeat Blood Cultures
Message-ID:
        
<[email protected]<mailto:[email protected]>>
Content-Type: text/plain; charset="us-ascii"

Hi All,

At University of California San Francisco Medical Center we are developing a 
standardized protocol for drawing blood cultures.  Do any of you have standards 
as to when blood culture can/should be drawn, especially repeat cultures.  Our 
clinicians advise not to draw repeat cultures in less than 24-48 hours.

Jim Stotts RN, MS, CNS
Sepsis Project Manager | Innovations In Population Health (DSRIP)
University of California San Francisco Medical Center
[email protected]<mailto:[email protected]><mailto:[email protected]<mailto:[email protected]>>
(c) 415-717-0098
(o) 415-514-8495

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Message: 2
Date: Thu, 24 Jan 2013 22:34:02 +0000
From: "Stotts, James" <[email protected]<mailto:[email protected]>>
To: 
"[email protected]<mailto:[email protected]>"
        
<[email protected]<mailto:[email protected]>>
Subject: [Sepsis Groups] Sepsis Screening in Oncology and Transplant
        Patients
Message-ID:
        
<[email protected]<mailto:[email protected]>>
Content-Type: text/plain; charset="us-ascii"

Hi All,

Does anyone have sepsis screening criteria that is tailored to Oncology or 
Transplant Patients that they would be willing to share?  We are looking to 
spreading sepsis screening from pilot units to the rest of the organization 
with a high volume of Oncology and Transplant patients, and are thinking that 
the usual SIRS criteria may miss or over identify patients as a positive screen.

Jim Stotts RN, MS, CNS
Sepsis Project Manager | Innovations In Population Health (DSRIP)
University of California San Francisco Medical Center
[email protected]<mailto:[email protected]><mailto:[email protected]<mailto:[email protected]>>
(c) 415-717-0098
(o) 415-514-8495

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Message: 3
Date: Wed, 23 Jan 2013 09:23:55 -0800
From: "Maurene Harvey" <[email protected]<mailto:[email protected]>>
To: 
<[email protected]<mailto:[email protected]>>
Subject: [Sepsis Groups] survivor resources
Message-ID: <[email protected]<http://gmail.com>>
Content-Type: text/plain; charset="us-ascii"

Are any of you providing sepsis survivors and their families with resources
to help them deal with potential long term consequences? The post acute care
community is largely unaware of what problems our patients and their
families might suffer.  Giving information to the patient and family might
help them understand what they are experiencing and lead them to seek out
appropriate care referrals.  Available resources include:

1.       Sepsis Alliance- sepsisalliance.org<http://sepsisalliance.org> - 
support for sepsis survivors

2.       ARDS Foundation- ardsusa.org<http://ardsusa.org> - support for ARD 
survivors

3.       SCCM MyICUCare - sccm.org<http://sccm.org> - information brochures for 
patients and
families including one on sepsis

4.       UK NICE Self-directed ICU recovery manual - 
nice.uk.org<http://nice.uk.org> -
recommendations for physical and cognitive recovery



SCCM has a task force working with stakeholders across the continuum of care
to address the issues and create more resources.



Thanks for all you do,

Maurene Harvey RN MPH MCCM

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Message: 4
Date: Wed, 23 Jan 2013 04:40:26 -0800 (PST)
From: seyed mohammad reza hashemian 
<[email protected]<mailto:[email protected]>>
To: Jeffrey R Hanlon RN <[email protected]<mailto:[email protected]>>,
        "[email protected]<mailto:[email protected]>" 
<[email protected]<mailto:[email protected]>>,
        "[email protected]<mailto:[email protected]>" 
<[email protected]<mailto:[email protected]>>
Cc: "[email protected]<mailto:[email protected]>" 
<[email protected]<mailto:[email protected]>>,
        
"[email protected]<mailto:[email protected]>"
        
<[email protected]<mailto:[email protected]>>
Subject: [Sepsis Groups] New Sepsis Guideline
Message-ID:
        
<[email protected]<mailto:[email protected]>>
Content-Type: text/plain; charset="utf-8"

Dear friends;
It was a?great ?day for Sepsis campaign group for presentation of new sepsis 
guideline here in SCCM congress ,if you like to read the new guideline and more 
details please see the? link:
?
Seyed Mohammadreza Hashemian.MD.FCCM
Associate professor of NRITLD/SBMU

http://www.survivingsepsis.org/Guidelines/Pages/default.aspx?

________________________________
 From: Jeffrey R Hanlon RN 
<[email protected]<mailto:[email protected]>>
To: [email protected]<mailto:[email protected]>; 
[email protected]<mailto:[email protected]>
Cc: [email protected]<mailto:[email protected]>; 
[email protected]<mailto:[email protected]>
Sent: Saturday, January 19, 2013 4:24 PM
Subject: Re: [Sepsis Groups] changing the sepsis screen for flu season


Again I think we are making this more complicated than it needs to be. If you 
are SIRS positive and have?a confirmed or suspected source YOU ARE SEPTIC by 
definition. Treat them or the mortality rate will continue to rise. The 
evidence is there.
Jeffrey R Hanlon RN
Stamp Out Sepsis
?
---- Original Message ----
From: Rich Levrault 
<[email protected]<mailto:[email protected]>>
To: Ron Daniels <[email protected]<mailto:[email protected]>>
Cc: sepsisgroups 
<[email protected]<mailto:[email protected]>>;
 Sue Beswick <[email protected]<mailto:[email protected]>>
Sent: Sat, Jan 19, 2013 1:17 pm
Subject: Re: [Sepsis Groups] changing the sepsis screen for flu season


Do facilities screen all pts w sirs and source at triage?? ?Our Ed is worried 
about over screening and the potential for sending labs on everyone. There are 
pts who present w fever and tachycardia who routinely don't have labs sent. 
?What are other facilities doing? ? Sean or Mitchell can you provide some 
backup for a former fellow who's pushing to cast a broad net and is advising to 
screen everyone? ?Ron...another sepsis guru .. Advice? I feel like I'm losing 
ground at our institution. ??

Rich Levrault

Sent from Rich's iPhone

On Jan 8, 2013, at 9:46 AM, Ron Daniels 
<[email protected]<mailto:[email protected]>> wrote:


If I could retweet this, I would!!
>
>
>The discussion is largely academic unless we have a viral PCR which is 100% 
>sensitive, 100% specific, and the results are available within the hour. In a 
>patient who clearly has evidence of impending or actual organ dysfunction, I'd 
>treat for both groups of pathogens until we know which is the culprit (and 
>even then we may not be convinced the virus is acting alone!)
>
>
>Ron
>
>
>On Mon, Jan 7, 2013 at 8:43 PM, Thomas Morris 
><[email protected]<mailto:[email protected]>> wrote:
>
>Dear Lisa
>>
>>Even though a virus, flu can also induce a cytokine storm, in fact this is 
>>apparently the mechanism by which people who are dying of influenza die. ?I'm 
>>sure 5 days of Antibiotics wouldn't cause much harm, indeed it would be quite 
>>hard to tell in the most severe cases and we do know that flu increases the 
>>chance of bacterial pneumonia
>>
>>Tom Morris
>>
>>Infectious Diseases SpR, Leicester
>>
>>
>>
>>On Sat, 5 Jan 2013 17:01:09 +0000
>>?"D'Amico, Lisa L" 
>><[email protected]<mailto:[email protected]>> wrote:
>>
>>If the patient is identified as having the flu are you still using 
>>antibiotics with the patient? ?Or are you using both antibiotic and antiviral?
>>>
>>>Lisa
>>>
>>>
>>>Lisa D'Amico, DNP, MSN, RN
>>>Clinical Quality Consultant
>>>Provider Engagement Performance Partnerships2
>>>Highmark, Inc.
>>>Fifth Avenue Place
>>>120 Fifth Avenue, Suite 893
>>>Pittsburgh PA 15222-3099
>>>Office:412-544-6804
>>>Fax:412-544-8135
>>>[email protected]<mailto:[email protected]>
>>>
>>>
>>>
>>>From: 
>>>[email protected]<mailto:[email protected]>
>>> 
>>>[mailto:[email protected]<mailto:[email protected]>]
>>> On Behalf Of Sara Valentine
>>>Sent: Thursday, January 03, 2013 3:53 PM
>>>To: 'Sue Beswick'; 
>>>[email protected]<mailto:[email protected]>
>>>Subject: Re: [Sepsis Groups] changing the sepsis screen for flu season
>>>
>>>When assessing for severe sepsis, we adjust our treatment (appropriate 
>>>volume of fluid and early antibiotics) depending on both assessment and 
>>>symptoms. So, for instance, if the patient does test positive for flu, and 
>>>has SIRS plus elevated lactate (>2.2-4) and/or new organ dysfunction, then 
>>>they are treated for severe sepsis, regardless of infection. If the flu is 
>>>the cause, just because it is viral doesn?t mean that it isn?t sepsis. Labs 
>>>we run initially are the same as yours. Lactic acid is a good indicator of 
>>>hypoperfusion, but doesn?t pertain just to sepsis, as lactic acid can be 
>>>elevated for other physiologic reasons. But according to the SSC Guidelines, 
>>>severe sepsis is defined as sepsis-induced tissue hypoperfusion or organ 
>>>dysfunction OR Lactate 2.2-4 mg/dL.
>>>
>>>
>>>Sara Valentine, BSN, RN, CNRN
>>>Nurse Educator/Clinical Sepsis Coordinator
>>>Medical Center Hospital
>>>500 West 4th Street
>>>Odessa, Texas ?79761
>>>ph: 432.640.1085
>>>fax:432.640.2885
>>>
>>>
>>>
From: 
[email protected]<mailto:[email protected]><mailto:[email protected]<mailto:[email protected]>>
 
[mailto:[email protected]<mailto:[email protected]>]
 On Behalf Of Sue Beswick
>>>
>>>Sent: Wednesday, January 02, 2013 2:21 PM
>>>To: 
>>>'[email protected]<mailto:[email protected]>'
>>>Subject: [Sepsis Groups] changing the sepsis screen for flu season
>>>
>>>Thank you all who responded. ?It was pretty clear that the majority do not 
>>>adjust your screen during the flu season.
>>>
>>>But related to that ? exactly what is your screen. ?Our is that when sepsis 
>>>criteria is met ? the RN gets a CBC with diff, serum lactate (we run on our 
>>>ABG machine), metabolic pane, the first bld culture, a UA/urine culture and 
>>>chest X-ray if resp symptoms.
>>>
>>>We are wondering if just the Lactate might be a good first step to rule out 
>>>severe sepsis and then treat the flu. ?Or do you do all the same tests/labs 
>>>that we do?
>>>
>>>Thanks
>>>Sue
>>>
>>>Sue Beswick RN, MS, CCNS, CCRN
>>>Clinical Nurse Specialist - MSICU
>>>Greenville Hosptial System
>>>University Medical Center
>>>Greenville, SC
>>>Office: ?864-455-4884
>>>
>>>AACN Theme "Dare To" ?What are you going to dare to do this year?
>>>
>>>________________________________
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>
>
>
>
--
>Dr Ron Daniels
>?
>
>CEO: Global Sepsis Alliance
>Chair: United Kingdom Sepsis Group
>
>Principal Trustee: U.K Sepsis Trust
>Founding Director: Survive Sepsis
>Fellow: NHS Improvement Faculty
>?
>?
>
>
>Suspect Sepsis: save someone's life today.
>
> Join us for World Sepsis Day on September 13th
>
>Twitter: @sepsisuk
>
>
>
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End of Sepsisgroups Digest, Vol 42, Issue 5
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