What did that do to the renal function?!

On Tue, 23 Apr 2013 21:33:34 -0400
 Rich Levrault <[email protected]> wrote:
As a fellow I presented a lit review on the use of hypertonic saline in resuscitation in sepsis and some interesting effects on cytokines and cellular adhesion molecules were noted(positive effects). I haven't looked at those data in a while but wanted to throw it out to the group. I was feeling a bit salty.
Sent from Rich's iPhone

On Apr 22, 2013, at 7:56 AM, "Thomas Morris" <[email protected]> wrote:

Hi Jeffrey

Thanks - although the Traumatic Brain Injury paper had patients on only 10hrly litre bags of NS for 48 hours, which is max. 4.8 litres - not that much is it? Surely you still have to "fill the gap" before, or at the same time as, getting someone on pressors?

I think it's a bit of a clinical evidence "hole" though, and personally I'm planning to use NS for the first 2 litres, then a bag of 5% dextrose (or possibly D/saline) for the 3rd litre, then flip a coin for what to give after that! Ie. crystalloid on one side, gelatin-based on the other! Or blood. No starch! And bring on the research for adjunctive immate immune system modulatory therapies.

Tom Morris
Infectious Disease/GIM Registrar


On Sat, 20 Apr 2013 19:43:25 -0400 (EDT)
that <[email protected]> wrote:
All of this must be taken in context of which bundle you are working in. Being an ED nurse, our main focus is in the resuscitation bundle and NSS is the fluid of choice. We have, on occasion, given albumin but that seems to be practitioner dependent. Plasma and PRBC's are next on the list, especially if your HCT is low. If you stick to EGDT and get your patient on pressors appropriately and start your broad spectrum antibiotics in a timely manner you probably won't have to worry about the hyperchloremic acidosis. If not it won't matter because the elevated lactate will get you to organ failure and death long before you need to worry about hyperchloremia.
Just my opinion. Jeffrey R Hanlon RN
Stamp Out Sepsis
-----Original Message-----
From: Katzaman, Alecia <[email protected]> To: '[email protected]' <[email protected]>
Sent: Tue, Apr 16, 2013 8:40 am
Subject: [Sepsis Groups] NSS vs Albumin
What does everyone do in terms of fluid resuscitation – do you give NSS or Albumin? What do you do in the ED? DO you have a limit of NSS that is given before Albumin is given, or is provider specific?
Alecia Katzaman, MSN, RN
Emergency Department Quality Improvement Coordinator
           P.O. Box 16052
           Reading, PA 19612-6052
[email protected]
www.readinghealth.org
PHONE: 484-628-4810
Advancing Health. Transforming Lives.
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