Hi, We do the usual dose of an aminoglycoside as well since you do have to load the patient. If treatment continues then we do dose adjustments going forward.
Martha J. Roberts, Pharm.D. Lead Clinical Pharmacist/Critical Care Specialist St. Joseph Health Services of RI 200 High Services Avenue No. Providence, RI 02904 (401) 456-3382 From: [email protected] [mailto:[email protected]] On Behalf Of Yash Javeri Sent: Wednesday, September 18, 2013 5:27 AM To: Harkey,Jessica Cc: [email protected] Subject: Re: [Sepsis Groups] Aminoglycoside dosing in severe sepsis/septic shock The dictum in antibiotic prescription is no change in loading dose of antibiotic with any co morbidity On 17-Sep-2013, at 22:57, "Harkey,Jessica" <[email protected]<mailto:[email protected]>> wrote: Hello there. I have been having some discussion with our pharmacists on whether or not patients who present to the ED in severe sepsis or septic shock should receive a full dose of an aminoglycoside (when indicated) within the first hour regardless of Cr clearance? The practice of our ED physicians thus far has been to order a full dose, and now we are getting some feedback from pharmacy to reduce the dose per renal function, which seems appropriate with consecutive doses along with monitoring drug levels. I am concerned about delaying administration. For initial empric therapy what are the rest of you doing in such cases? Any literature available for me to share with the pharmacy? Thank you! Jessica Harkey, RN, BSN, CCRN Sepsis Program Coordinator San Joaquin Community Hospital 661-869-6874 [email protected]<mailto:[email protected]> <image001.png> _______________________________________________ Sepsisgroups mailing list [email protected]<mailto:[email protected]> http://lists.sepsisgroups.org/listinfo.cgi/sepsisgroups-sepsisgroups.org
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