Hi there. So far I have yet to see the need for transfusions in our population 
in order to achieve that target specifically for sepsis alone in the absence of 
blood loss or underlying anemia. We try to support tissue oxygenation in severe 
sepsis by addressing fluid status FIRST, and then look at  availability 
(supplemental O2? NIPPV? Intubation?), O2 carrying capacity (Hct?) and also 
delivery (myocardial dysfunction/need for inotropic support). Transfusion is 
not typically the first line to address an ScVO2 of less than 70%. From my 
experience I have seen this target achieved with continuing fluid boluses, 
especially when the CVP is not at target.

Jessica Harkey, RN, BSN, CCRN
Sepsis Program Coordinator
San Joaquin Community Hospital
661-869-6874
[email protected]<mailto:[email protected]>
[Description: wr]

From: [email protected] 
[mailto:[email protected]] On Behalf Of Daniel Gerard
Sent: Wednesday, October 02, 2013 1:01 PM
To: [email protected]
Subject: [Sepsis Groups] blood

I'm having some difficulty understanding the role of transfusion with the new 
sepsis guidelines. Are people still using transfusions in patients with HCT 
less than 30 during the initial 6 hours to increase ScV02 ?

Daniel Gerard RPh
Critical Care Pharmacist
McClaren-Northern Michigan
Phone: 231-487-4770
FAX: 231-487-4817
[email protected]<mailto:[email protected]>


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