We do not draw blood culture from the central line source due to natural 
contaminate.  Always draw from percutaneous sites.

From: Sepsisgroups [mailto:[email protected]] On 
Behalf Of Angela Craig
Sent: Friday, July 31, 2015 6:02 AM
To: '[email protected]'
Subject: [Sepsis Groups] Blood Cultures from Central Lines


Is everyone out there getting one set of blood cultures from the central line 
if the line has been placed >48 hours? per the guidelines (see below)?

If so - have you seen an increase in your CLABSI rates due to the risk of false 
positive blood cultures when collected from the line??  Anyone getting 
encouragement from Infection Control to only get cultures if the line is the 
suspected source per IDSA/CDC guidelines??


C. Diagnosis

1. Cultures as clinically appropriate before antimicrobial therapy if no 
significant delay (> 45 mins) in the start of antimicrobial(s) (grade 1C). At 
least 2 sets of blood cultures (both aerobic and anaerobic bottles) be obtained 
before antimicrobial therapy with at least 1 drawn percutaneously and 1 drawn 
through each vascular access device, unless the device was recently (<48 hrs) 
inserted (grade 1C).



Angela Craig  APN, MS, CCNS
CNS for ICU
Cookeville Regional Medical Center
931-783-5035




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