The decision to measure the application of vasopressors is unfortunate in my 
view.

However, since it is measured, it is important to recall that the any time a 
vasopressor is applied, the goal is to wean it, not maintain it.  Thus while 
the measure checks to see that vasopressors were applied (ostensibly to prevent 
imminent cardiovascular collapse) they can be immediately weaned to off as long 
as MAP > 65, perhaps with additional fluids.

On Nov 2, 2015, at 9:52 AM, Myran, Robin 
<[email protected]<mailto:[email protected]>> wrote:

All –

I submitted this question through QualityNet, but was interested in your 
thoughts…

The sepsis protocol at our hospital includes the administration of 30 cc/kg 
crystalloid for hypotension or lactate >=4. If the patient remains hypotensive 
after the initial bolus, we have the option of administering an additional 30 
cc/kg. Often this second bolus works to achieve a sustained MAP >=65.

According to the specifications manual for SEP-1, we *must* start a vasopressor 
by the 6th hour if the patient remains hypotensive in the hour after the 
initial bolus is complete, correct? The Surviving Sepsis Campaign's 
recommendations include "a minimum of 30 mL/kg of crystalloids" and that 
"greater amounts of fluid may be needed in some patients." They go on to say 
that "fluid administration is continued as long as there is hemodynamic 
improvement". My physicians will always go to more fluids first (if the patient 
remains fluid responsive) before starting vasopressors. Can you provide 
additional information/clarification so I can educate my clinicians?


Robin Myran, MSN, RN, PCCN
Sepsis Coordinator
Hoag Memorial Hospital Presbyterian
One Hoag Drive
Newport Beach, CA 92658
Office: (949) 764-4588
Fax: (949) 764-5387
Cell: (949) 300-9137
[email protected]<mailto:[email protected]>


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