Sepsis in Children During the COVID-19 Pandemic
Listen to Mark Peters, MD, 
PhD<https://sccmvoices.gv-one.com/video.html?v=YSaFZXElTgw=&token=93b5ce04e8032b8a6adbd8ee5a157a4c>
 discuss the latest update in PCCM online, Perspective of the Surviving Sepsis 
Campaign on the Management of Peds Sepsis in the Era of COVID-19

<http://SCCM.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MTk/index.html>[PPE
 Strategies for the COVID-19 
Era]<http://sccm.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MTk/index.html><http://SCCM.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MTk/index.html><http://sccm.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MTk/index.html><http://SCCM.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MTk/index.html>

In the COVID-19 era, clinicians must navigate additional diagnoses in the early 
identification and treatment of 
sepsis<http://SCCM.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MjA/index.html>.



Children infected with severe acute respiratory syndrome coronavirus 2 
(SARS-CoV-2) can present with sepsis or septic shock. COVID-19 and multisystem 
inflammatory syndrome in 
children<http://SCCM.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MjE/index.html>
 (MIS-C) must now be considered as possible diagnoses for acutely ill children 
who present with features of sepsis.



Members of the Surviving Sepsis Campaign 
(SSC)<http://SCCM.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MjI/index.html>
 children's sepsis guidelines task force offer their perspectives on treating 
children in the COVID-19 era in this Pediatric Critical Care Medicine (PCCM) 
article<http://SCCM.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MjA/index.html>.




Here is what you need to know:

  *   Continue to use the SSC children's 
guidelines<http://SCCM.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MjI/index.html>
 as the framework for early recognition and initial resuscitation when treating 
sepsis in acutely ill children.
  *   Consider the novel diagnosis of SARS-CoV-2 when evaluating children for 
sepsis or septic shock.
  *   Apply a systematic process to clinical assessment and be aware of bias or 
fixation on a COVID-19 or MIS-C diagnosis.
  *   When treating patients with suspected COVID-19 and MIS-C, remember to 
keep sepsis in the list of possible diagnoses. If the patient ultimately has 
sepsis from COVID-19, another infection, or MIS-C, follow the six key 
management 
steps<http://SCCM.informz.net/z/cjUucD9taT05NTIwNDE1JnA9MSZ1PTEwODM2Mjc1MjkmbGk9Nzk2Mjk3MTk/index.html>.
  *   The potential benefits of adjunctive therapies may differ between sepsis 
caused by SARS-CoV-2 and other pathogens. Given the uncertainty, it is best to 
consult with additional subspecialists.
  *   Do your part to raise awareness about sepsis symptoms among parents and 
caregivers of patients with COVID-19 or MIS-C. Parents should be aware of the 
risks and early symptoms of sepsis.

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