On Friday 05 Feb 2010 12:15:16 am Pranesh Prakash wrote:
> Science is many things to many people, but any lab-rat will tell you
> that research is mainly long stretches of frustration, interspersed with
> flashes of satisfying success. [The best laid schemes of mice and men
> gang aft agley][2]. A scientist’s path contains leads to blind alleys
> more than anything else, and meticulous experimental preparation only
> serves to somehow mitigate the problem, if you’re lucky. *This doesn’t
> work, that doesn’t work either and this technique worked perfectly in
> Dr. X’s lab, why can’t I get this to work for me?  My experiment was
> invalidated by my controls; my controls didn’t work the way the controls
> were supposed to work in the first place. I keep getting weird results
> from this assay. I can’t explain my latest results in any coherent way*…
> these statements are typical of daily life in the lab.

I read a paper on the frustration of reasearch maybe 28 years ago - I had 
summarized the paper on silk list in 1998

http://groups.yahoo.com/group/silk-list/message/813

shiv

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