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  From: Dianne France 
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  NEWS RELEASE FROM THE AMERICAN CHEMICAL SOCIETY:
  "Catnip Repels Mosquitoes More Effectively Than DEET" 

  CHICAGO, August 27, 2001 - Researchers report that nepetalactone, the 
essential oil in catnip that gives the plant its characteristic odor, is about 
ten times more effective at repelling mosquitoes than DEET - the compound used 
in most commercial insect repellents. 
  The finding was reported today at the 222nd national meeting of the American 
Chemical Society, the world's largest scientific society, by the same Iowa 
State University research group that two years ago discovered that catnip also 
repels cockroaches. 

  Entomologist Chris Peterson, Ph.D., with Joel Coats, Ph.D., chair of the 
university's entomology department, led the effort to test catnip's ability to 
repel mosquitoes. Peterson, a former post-doctoral research associate at the 
school, is now with the U.S. Department of Agriculture Forest Service, Wood 
Products Insects Research Unit, in Starkville, Miss. 
  While they used so-called yellow fever mosquitoes (Aedes aegypti) - one of 
several species of mosquitoes found in the United States - Peterson says catnip 
should work against all types of mosquitoes. 

  Aedes aegypti, which can carry the yellow fever virus from one host to 
another, is found in most parts of the United States. Yellow fever itself, 
however, only occurs in Africa and South America, according to the Centers for 
Disease Control. Vaccines and mosquito control programs have essentially wiped 
out the disease in the United States, although there have been isolated reports 
of unvaccinated travelers returning with the disease. The last reported 
outbreak in this country was in 1905. 
  Peterson put groups of 20 mosquitoes in a two-foot glass tube, half of which 
was treated with nepetalactone. After 10 minutes, only an average of 20 percent 
- about four mosquitoes - remained on the side of the tube treated with a high 
dose (1.0 percent) of the oil. In the low-dose test (0.1 percent) with 
nepetalactone, an average of 25 percent - five mosquitoes - stayed on the 
treated side. The same tests with DEET (diethyl-m-toluamide) resulted in 
approximately 40 percent to 45 percent - eight-nine mosquitoes - remaining on 
the treated side. 

  In the laboratory, repellency is measured on a scale ranging from +100 
percent, considered highly repellent, to -100 percent, considered a strong 
attractant. A compound with a +100 percent repellency rating would repel all 
mosquitoes, while -100 percent would attract them all. 
  A rating of zero means half of the insects would stay on the treated side and 
half on the untreated side. In Peterson's tests, catnip ranged from +49 percent 
to +59 percent at high doses, and +39 percent to +53 percent at low doses. By 
comparison, at the same doses, DEET's repellency was only about +10 percent in 
this bioassay, he notes. 
  Peterson says nepetalactone is about 10 times more effective than DEET 
because it takes about one-tenth as much nepetalactone as DEET to have the same 
effect. 

  Most commercial insect repellents contain about 5 percent to 25 percent DEET. 
Presumably, much less catnip oil would be needed in a formulation to have the 
same level of repellency as a DEET-based repellent. 
  Why catnip repels mosquitoes is still a mystery, says Peterson. "It might 
simply be acting as an irritant or they don't like the smell. But nobody really 
knows why insect repellents work." 

  No animal or human tests are yet scheduled for nepetalactone, although 
Peterson is hopeful that will take place in the future. 
  If subsequent testing shows nepetalactone is safe for people, Peterson thinks 
it would not be too difficult to commercialize it as an insect repellent. 
Extracting nepetalactone oil from catnip is fairly easily, he says. "Any high 
school science lab would have the equipment to distill this, and on the 
industrial scale it's quite easy." 

  Catnip is a perennial herb belonging to the mint family and grows wild in 
most parts of the United States, although it also is cultivated for commercial 
use. Catnip is native to Europe and was introduced to this country in the late 
18th century. It is primarily known for the stimulating effect it has on cats, 
although some people use the leaves in tea, as a meat tenderizer and even as a 
folk treatment for fevers, colds, cramps and migraines. 
  A patent application for the use of catnip compounds as insect repellents was 
submitted last year by the Iowa State University Research Foundation. Funding 
for the research was from the Iowa Agriculture Experiment Station. 

  Chris Peterson, Ph.D., is a former post-doctoral research associate at Iowa 
State University in Ames, Iowa, and is now a Research Entomologist with the 
U.S. Department of Agriculture Forest Service, Wood Products Insect Research 
Service, in Starkville, Miss. 
  Joel R. Coats, Ph.D., is professor of entomology and toxicology and Chair of 
the Department of Entomology at Iowa State University in Ames, Iowa." 

  Note: This story has been adapted from a news release issued by American 
Chemical Society for journalists and other members of the public. If you wish 
to quote from any part of this story, please credit American Chemical Society 
as the original source.