Very Interesting. Thank you. -----Original Message----- From: Rowena [mailto:new...@aapt.net.au] Sent: Wednesday, September 03, 2008 8:37 AM To: silver-list@eskimo.com Subject: CS>Bacteria & Mental Illness & Cancer Part 2
Part 2 Scientists who have extensively studied the cancer microbe claim it most closely resembles the type bacteria that cause tuberculosis and leprosy- the so-called mycobacteria. Mycobacteria are closely related to fungi; and some microbiologists claim mycobacteria are essentially derived from the "higher" fungi. "Myco" in Greek means fungus. Ergo, mycobacteria are onsidered fungus-like bacteria. Photo #6: Extremely large "super-giant-sized" solitary Russell body in the skin of "cutaneous lupus erythematosus", a so-called "collagen disease." The perfectly round shape, except for one area, suggests this large body is developing inside a cell that is readly to burst. Kinyoun's (acid-fast) stain, magnification x 1000. During the 1960s microbiologist Louis Dienes popularized the terms "cell wall-deficient" and "L form" to encompass bacterial growth stages that exist at one extreme as small filterable virus-sized forms, and at the opposite extreme as large (50 micron or larger) spherical forms that he termed "large bodies." These so-called large bodies are what I believe Russell bodies represent. It must be understood that microbes are partially "classified" in microbiology according to size. Viruses are submicroscopic and cannot be visualized with an ordinary light microscope. Unlike bacteria, viruses can only replicate inside a cell. Bacteria can be seen microscopically, but smaller submicroscopic and filterable bacterial forms (now known as nanobacteria) are also known. Fungi and yeast forms are much larger than bacteria, and "mold" can obviously be seen with the naked eye. Larger Russell bodies are indeed similar in size to certain spore forms of fungi. However, what is generally not appreciated is that bacteria can grow into fungal-sized large bodies, depending on certain laboratory conditions. Thus, bacteria in this form can easily be mistaken for fungi and yeast organisms. Giant-sized L-forms greatly resemble large-sized Russell bodies. The century-old history of research into atypical growth forms of bacteria is reviewed in Lida Mattman's seminal text, Cell Wall Deficient Forms: Stealth Pathogens (1993). A knowledge of this somewhat esoteric branch of microbiology is essential to understand the proposed microbiology of cancer. The most impressive electron microscopic photographs I have ever observed of cell wall-deficient L-forms of mycobacteria were taken by the late C Xalabarder of Barcelona. In a series of papers and books (1953-1976) published in Spanish (with English-language summaries) by the Publicaciones del Instituto Antituberculoso "Francisco Moragas", Xalabarder totally transformed my concept about how tuberculosis- causing mycobacteria reproduce and grow and drastically change their appearance. In medical school we were taught that "simple" bacteria simply divide in two equal halves by "binary fission". However, nothing could be further from the truth, and it is only by a refutation of this simplistic concept that a serious study of the microbiology of cancer can be undertaken. Tuberculosis and Cancer Because cancer is produced by a microbe similar to the bacteria that cause TB, much can be learned from experiments like those performed by Xalabarder in 1967. Using "atypical mycobacteria" grown from TB patients who had taken long courses of drug therapy, Xalabarder then injected these bacteria into guinea-pigs and rabbits. Amazingly, he was able to experimentally produce lesions which microscopically resembled cancer! He also produced experimental lesions characteristic of so called "collagen disease"- a type of lesion seemingly unrelated to cancer. During the 1960s I discovered unusual pleomorphic acid-fast bacteria in a collagen disease called scleroderma, and later in another collagen disease called lupus erythematosus. The germs I grew from these patients closely resembled scleroderma microbes that were reported by Virginia Livingston in 1947, and which subsequently led to her discovery of similar acid-fast microbes in cancer. In 1969 Xalabarder manipulated different developmental stages of TB bacteria and inoculated them into one thousand guinea pigs. In the process, he produced the microscopic picture of sarcoidosis in the animals. Sarcoidosis is a human disease closely related to TB but one in which TB germs cannot be found. Xalabarder's most impressive sarcoid lesions were produced by inoculating sputum specimens from TB patients who "converted", meaning that their TB bacteria could no longer be cultured from their sputum. Controversy over the cause of sarcoidosis is still not settled, although I reported bacteria similar to cancer microbes in this disease in the 1980s. The most spectacular electron microphotographs of cell wall-deficient mycobacteria are presented in Xalabarder's L-forms of mycobacteria and chronic nephritis (1970). In the earliest growth stages of mycobacteria in culture the smallest elements appear as tiny submicroscopic forms visualized only with the electron microscope. These filterable forms of tuberculosis bacteria - the so-called "tuberculosis virus"- have been known to cause cancer in animals since the 1920s. By adding antibiotics to the lab culture media Xalabarder was able to induce many unusual growth forms of tuberculosis bacteria. Using serial images, he was able to trace the development of these tiny submicroscopic forms up to the size of ordinary cocci - and then up to the size of "large body" forms reaching and even surpassing the size of red blood cells. Some of the large bodies of mycobacteria also exhibit internal structure, similar to what Gaylord noted in his Russell body research. Cancer and Bacteria Although the idea of a cancer microbe is medical heresy, there is ample data to show that cancer patients are highly prone to bacterial infection. A PubMed computer search (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi) of "bacteria + cancer" elicits 49, 244 citations contained within 2,463 web pages. According to a 2003 article by Vento and Cainelli, patients with cancer who are undergoing chemotherapy are highly susceptible to almost any type of bacterial or fungal infection. Why are physicians, and especially pathologists and bacteriologists, so unaware, so disinterested, or so antagonistic to credible cancer microbe research? Why have pathologists failed to consider Russell bodies as large forms of bacteria? For over 30 years I studied various forms of cancer and skin diseases "of unknown origin", as well as autopsy cases of cancer, lupus, scleroderma, and AIDS. In all these diseases I was able to detect bacteria, although pathologists would never mention bacteria in any of their official biopsy reports. In my experience, they simply could not conceive of cancer and collagen disease (and AIDS) as a bacterial infection, nor did they seem to be aware of bacteriology reports pertaining to "large bodies" and pathologic effects produced by the "tuberculosis virus." In short, they were trained to see and report only the typical rod-shaped acid-fast (red-stained) "typical" form of mycobacteria, , but they were not trained to look for or to recognize other growth forms of the same bacteria that might be hidden in their pathologic tissue specimens. Photo #7: Pleomorphic growth forms (L-forms) of tuberculosis mycobacteria photographed with an electron microscope. Note the darker staining tiny coccal forms (similar in size to ordinary staphylococci) and the larger clear balloon-sized "ghost" forms similar in size and shape to Russell bodies found in tissue. These forms are all characteristic of "cell wall-deficient bacteria" and totally unlike the well-known "typical" acid-fast rod forms of Mycobacterium tuberculosis. Reproduced from L-forms of Mycobacteria and Chronic Nephritis (1970), by Dr. C. Xalabarder P., page 51. When objects like Russell bodies are observed in a wide variety of diseases and in "normal" tissue, the significance is lessened. Doctors expect "normal" tissue to be free of microbes. I suppose they also conclude that Russell bodies cannot be an infectious agent because it would be impossible for an infectious agent to appear in so many different kinds of diseases and in so many different forms of cancer. For most of the last century stomach ulcers were thought to be non-infectious because pathologists could not identify bacteria in the ulcers and because doctors believed bacteria could not live in the acid environment of the stomach. This thinking all changed gradually after 1982 when Barry Marshall, an Australian physician, proved most stomach ulcers were caused by a microbe called Helicobacter pylori, which could be identified microscopically with special tissue staining techniques in ulcer tissue. On the other hand, many people normally carry this stomach microbe without any ill effects. Not surprisingly, pathologists are now reporting numerous Russell bodies in plasma cells in some ulcer patients, giving rise to a previously unrecognized tissue reaction called "Russell cell gastritis." Russell bodies and bacteria When bacteria are threatened by the immune system or by antibiotics they may lose their cell-wall and assume a different growth form that renders them less susceptible to attack by the immune system. Some Russell bodies elicit little or no inflammatory cell response. This lack of cellular response is yet another reason why physicians have a hard time believing Russell bodies could be microbes. I have observed the largest and most complex Russell bodies in tissue where there was almost a total lack of inflammation. My photographs of such "large bodies", some with obvious internal structure, that I observed in patients with scleroderma and pseudoscleroderma, were published in the American Journal of Dermatopathology in 1980. The first case of fatal scleroderma I studied in 1963 had numerous "large bodies" in the fat layer of the diseased skin that were unlike anything ever seen in dermatology. The patient had been hospitalized for pulmonary tuberculosis 7 years before developing scleroderma. The mystery of these "yeast-like" bodies deep in his skin was solved years later when I first learned about the existence of "large body" forms of Mycobacterium tuberculosis. When this patient died, Mycobacterium fortuitum, an "atypical" form of mycobacteria was cultured from his scleroderma tissue. Bacteria are vital for our survival. They are hardy and the bacteria we carry will surely outlive us. The bacteria that cause cancer are the "simple" bacteria we carry with us. The cancer microbe is not an exotic microbe nor a rare one. However, bacteria can change form as the environment in our bodies changes. There is indeed a delicate balance between our bacteria and our immune system which allows these bacteria to live in harmony with us. But when dis-ease occurs these microbes become aggressive, giving rise to a host of diseases, some of which are cancerous, and others that are inflammatory, degenerative, or simply transitory. Another reason for physicians to doubt that a single type of germ could cause such a variety of pathologic effects. Bacteria are ubiquitous and so are Russell bodies. And if Russell bodies prove to be bacteria, the reason for this becomes obvious. The Russell body and the origin of cancer In 1981 King and Eisenberg's article on "Russell's fuchsin body: 'The characteristic organism of cancer' " appeared in the American Journal of Dermatopathology. They reconfirmed that "Russell bodies have now been shown to be immunoglobulins." They remarked that Russell was not the first to describe them; and that similar bodies were reported by Cornil and Alvarez in rhinoscleroma five years earlier in a French journal in 1885. Declaring it ironic that these "bodies should bear the name of a man who so thoroughly misunderstood them", the authors ended by stating: "Hence, when the term Russell body is used today, one should be aware that the eponym is as inaccurate as was Russell's perception of their significance." Unlike King and Eisenberg, I believe Russell was right on the mark. There is a parasite in cancer. It has been studied and reported by various scientists throughout the world for many decades, and a wealth of scientific information on the cancer microbe is available in medical libraries. For those with Internet capability, the words "cancer microbe" typed into Google.com will give instant access to a treasure trove of information on the subject. There is no secret to cancer. In my view, the cause is staring us right in the face in the form of the Russell body. William Russell understood very well in the nineteenth century what medical science in the twenty-first century has yet to discover. Alan Cantwell, M.D. is a retired dermatologist and cancer researcher. His book, The Cancer Microbe, is available through Internet sources. A number of his full-length papers on the microbiology of cancer can be found on the net at the Journal of Independent Medical Research web site (www.joimr.org/) Email: alanr...@aol.com MainPage http://www.rense.com -- The Silver List is a moderated forum for discussing Colloidal Silver. Instructions for unsubscribing are posted at: http://silverlist.org To post, address your message to: silver-list@eskimo.com Address Off-Topic messages to: silver-off-topic-l...@eskimo.com The Silver List and Off Topic List archives are currently down... List maintainer: Mike Devour <mdev...@eskimo.com>
