I'd be very cautious when nebulizing DMSO on a smoker. It could release
a lot
of the stored poisons coating the lungs from smoking. Below is a message
from Brooks
Bradley:
Date: Tue, 17 Apr 2001 21:34:54 -0500
From: BROOKS BRADLEY
Subject: Re: CS>Caution using H2O2/CS Inhalation Therapy
To all interested listmembers:
I have followed the recxent postings relative to incorporating H202 into
the pulmonary system protocol involving nebulization. After inquiring
from some of our staff involved in some of our evaluations several years
ago ... I am informed that CAUTION is the watchword when dealing with
unknown pathogenic parameters.
I am informed that pronounced adverse reactions occurred in some of our
animal evaluations. The problem was determined to be based upon the
nature/condition of the biological terrain of the lungs --- AT THE TIME
OF INHALATION. It seems that, although, the air sacs are superficially
exposed to atmospheric 02 on every inhalation (excepting those
compromised by anerobic pathogens insulated from this high O2 gas (air)
... there exists a circumstance presenting serious challenges to the
UNREGULATED exposure to H202.
The systemic challenge can manifest if sufficient volume of the H202
mist comes into sudden...direct contact with ANY sizeable anerobic
population If there is a sizeable population of anerobes present
---WHICH PRESENT IMMEDIATE ACCESSIBLITY to the incoming H202 mist ...
the possibility exists that the foaming action could be great enough to
generate SERIOUS consequences.
This possibility rises by an order of magnitude if DMSO is involved in
the protocol. Our staff confirmed this through animal experiments.
Adverse reactions were encountered in some cases involving H202
concentrations as low as 2%. The stabilizing protocol involved 100% 02
at 1.25 atmospheres --- and was instituted at the FIRST signs of
pulmonary distress.
In my opinion, administering CS in combination with H202 --- into an
unknown pathogenic environment involving the lungs --- could be VERY
serious. I am not attempting to be alarmist in this instance; just
pointing out what should be obvious to all deliberate/cautious
researchers. The odds against a serious adverse occurrence are,
probably, higher than its likelihood ... but even long odds are not too
desireable when the breathing system is involved.
If one insists on experimenting with such a protocol, it would appear
prudent to start at or below 0.5% H202. It would, also, be adviseable
to mix a sample of the volunteer's sputum with a generous amount of your
protocol solution and observe for reaction ... prior to inducing
inhalation procedures.
Sincerely, Brooks Bradley.
--
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