This will be of considerable interest I think .
Judith.
Subject: Fwd: Concerns over chemicals in cosmetics

This is a big concern, and whenever possible drinks should come from
glass bottles.


Concerns over chemicals in cosmetics . Are 'plasticizing' substances
causing health woes?
By Francesca Lyman
SPECIAL TO MSNBC
 Oct. 4 - Beauty is only skin deep, but a new study suggests that
some common cosmetic products leave traces of "plasticizing" chemicals
in   our bodies that could cause an array of health woes. Such
research is  adding momentum to a movement calling for better
monitoring of  environmental toxins and any harm they could be causing
to our health.
<http://www.msnbc.com/news/472235.asp?0nm#BODY
<http://www.msnbc.com/news/YOURENVIRONMENTH_Front.aspFrancesca Lyman's
Your Environment Archive
<http://www.msnbc.com/bbs/health.aspPost your views on MSNBC's Health
Bulletin Board
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 WHEN CERTAIN chemicals in a class known as phthalates, used to
soften vinyl plastic, were found to leach out of baby rattles and
teethers several years ago, it touched off a controversy that led to
bans  and voluntary recalls in the toy industry. Regulators started
reassessing  the safety of these chemicals, which some investigators
suspect of
 causing cancer and birth defects. Now, researchers at the Centers for
Disease Control and Prevention  report in the October issue of the
journal Environmental Health  Perspectives that the average American
may be exposed to other chemicals  in the phthalate family -
substances shown to cause cancer, birth defects  and adverse hormonal
effects in lab animals.

The researchers detected surprisingly higher levels of these
plasticizers than of toxins often tested for, such as lead or
polychlorinated biphenyls (PCBs) - and much higher than the other
phthalates that had been most controversial - in random urine samples
taken of the American population. They concluded that it was
"critically  important" to get further exposure data on these
chemicals, used in  cosmetics, and a wide variety of other consumer
products, in order to  assess health risks to people, especially
"potentially susceptible  populations."

Phthalates, chemicals that off-gas from plastic (familiarly
associated with "new car smell") are used in scores of consumer
products  - everything from perfumes and hair sprays to artificial
leather and  garden hoses, hair sprays and lotions to shower curtains
and vinyl flooring.    With up to 4 million tons of phthalates
produced and widely used
 throughout the world each year, industry representatives downplay any
adverse effects to human health.

NEW RESEARCH
The new study, done by CDC's [Centre for Disease Control] National
Center for Environmental  Health, represents the first time
researchers have measured the presence  of phthalates in humans. "It's
an important study," says Mike Shelby,  chief of the toxicology
laboratory at the National Institute of  Environmental Health Sciences
(NIEHS), "because it shows for the first  time how much of these
compounds people are really being exposed to."

 Find the phthalates
. Di-ethyl phthalate: Toothbrushes, auto parts, tools, toys, food
packaging, insecticides, mosquito repellents, aspirin and volatile
components of cosmetics -- perfumes, nail polishes and hair sprays.
. Di-n-butyl phthalate: Cellulose plastics, solvents for dyes,
solvents for cosmetics (i.e., nail polish), food wrap, perfumes, skin
emollients, hair spray, insect repellents.
. Benzyl butyl phthalate: Plasticizers in adhesives, PVC flooring,
wood finishes, biodegradable tampon ejectors
Sources: ATSDR, CDC, Industry sources

 The results, he says, show both that people are being exposed on a
wide scale and that "those with the highest levels are getting higher
doses than we thought."    While the highest doses are at levels "much
lower than where you'd  see toxic effects in rodents," says Shelby,
"it's when those two start  approaching one another that you start to
worry."

More research is already underway on a bigger sampling of the
population, with more tests needed to better determine what health
effects phthalates might cause in people or developing fetuses.    Yet
these preliminary findings add to concerns that "background"  levels
of many chemicals in the environment - long thought to be in small
 enough concentrations to have negligible effects on human health -
could  play a crucial role in human development as well as in causing
cancer,  neurological, immune system disorders and infertility, says
Jim O'Hara,  director of Health Track, a new nonprofit group funded by
the Pew  Charitable Trusts trying to build support for better
"exposure" monitoring.

 "What this study points to," says O'Hara, "is that there's a
significant gap in our knowledge of what levels people have of toxic
substances."

His views echo those of the Pew Environmental Health Commission,
which has charged that the nation faces an "environmental health gap."
In  September the commission called on Congress to mount a new program
to
 effectively track and monitor the chronic diseases that stem from
environmental pollution - everything from asthma and chronic
respiratory  diseases to birth defects and developmental disorders to
multiple  sclerosis and Parkinson's. While "overt poisoning from
environmental  toxins has long been recognized, the environmental
links to a broad array  of chronic diseases of uncertain cause is
unknown," the Commission wrote.

CDC chemist John Brock, the lead researcher on the phthalate  study,
came upon his discovery by accident. While he was looking for  known
carcinogens such as PCBs in blood and urine, he discovered  phthalates
present at levels 1,000 times higher than PCBs. Metabolites of diethyl
phthalate (DEP), used in volatile  components of cosmetics like
perfumes, nail polishes and hairsprays, were  found at levels about 70
times higher than metabolites of
 di-(2-ethylhexyl) phthalate (DEHP), one of the chemicals banned in
soft  plastic toys, for example.

"Phthalates are everywhere in the lab, in the vials, the tubing,  and
the syringes," says NIEHS's Shelby. "So we routinely shrugged them
off as contaminants." But Brock was compelled by the question: What if
they weren't just contaminants, but rather residues of chemical
exposures  in the environment from the widespread use of phthalates
from a variety  of routes - through food and drink, skin absorption or
inhalation, for example?

"Everyone was looking for the needle in the haystack, when what  they
should have been looking at was the hay," says Brock. He went on to
prove in ongoing studies over the past few years that the
"troublingly"  high levels of phthalates he detected in humans weren't
coming from soft  plastic tubing but from chemicals used in a wide
range of products,  ranging from nail polishes and perfumes, hand
lotions and soaps, to wood  finishes.

By tracing the human metabolites of these chemicals - the  breakdown
products in the human body - "we've been able to get really  accurate
numbers on how average Americans are being exposed," Brock says.

STUDY DETAILS
 In the study, researchers measured the levels of seven phthalate
metabolites in urine samples taken from 289 people. The researchers
are  now following up on an additional 1,000 subjects to better
ascertain the  sources of the phthalates. At this point, says Brock,
it's certainly not clear what health  effects the phthalates may have
on the subjects. However, his biggest  concern was that "the highest
levels of exposure were in women of
 child-bearing age."

 Healthy discussion
Talk about the issues
<http://bbs.msnbc.com/bbs/msnbc-health/index.asp.
<http://bbs.msnbc.com/bbs/msnbc-health/index.aspHealth Bulletin Board
 Reproductive biologist Earl Gray of the Environmental Protection
Agency, who studied the effects of phthalates on rodents, says that
there's ample cause for concern as the chemicals are reproductive
toxins,  with two, DBP and BzBP, particularly anti-androgenic, tending
to block  male hormones. "The effects on rats were quite profound,
creating  malformed genitalia, vaginal pouches, absent or undescended
testes, and  infertility," says Gray.

The industry-sponsored Phthalate Esters Panel, while praising the
study for its use of the latest diagnostic chemical techniques, said
the  phthalate levels uncovered in the CDC study are of "negligible"
concern.   In a letter to CDC, the Panel's toxicologist Raymond M.
David  suggested using a formula that could take the new urine data
and  extrapolate "intake" levels of the phthalates based on data from
human  volunteers in Britain.   With this formula, he found the
"intake" exposures to be "at or  below levels that the EPA has
determined to be safe for daily exposures."

PROTECTING OUR HEALTH
 Others, however, took the findings as a sign that the current
regulatory regime is not protecting public health. "This study reveals
that exposures are real, and that we've neglected the vital work of
testing our own bodies for pollutants in the environment," says J. P.
Myers, one of the co-authors of the book "Our Stolen Future," which
 proposed that hormone-disrupting chemicals in the environment might
be  producing cancers and other ill effects. "For a long time we've
been  depending on safety limits developed by engineers and based on
 assumptions that are probably wrong."






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