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From: PlusNews <[email protected]>
Date: Thu, Dec 1, 2011 at 2:32 PM
Subject: HEALTH: TB programming, research slowed by inadequate funding
To: Elisabeth Janaina <[email protected]>


HEALTH: TB programming, research slowed by inadequate funding

NAIROBI, 1 December 2011 (PLUSNEWS) - The number of people dying from
tuberculosis fell to its lowest level in a decade in 2010, but experts
warn that a shortfall of US$1 billion for TB programmes in 2012, and
the recent cancellation of funding by the Global Fund to fight AIDS,
TB and Malaria, threaten these gains.

 According to the UN World Health Organization's (WHO) 2011 Global
Tuberculosis Control Report [
http://www.who.int/tb/publications/global_report/2011/gtbr11_full.pdf
], the number of people with TB dropped to 8.8 million in 2010, from a
peak of nine million in 2005, while deaths fell to 1.4 million in 2010
from 1.8 million in 2003.

 TB is a leading cause of death for people living with HIV in Africa;
WHO reports that 44 percent of TB patients in Africa tested for HIV in
2010 were positive.

 WHO reports that funding from domestic and donor sources is expected
to amount to $4.4 billion in 2012, up from $3.5 billion in 2006;
however, countries are reporting funding gaps of close to $1 billion
in 2012.

 "Continued gaps in funding mean that many people with TB will
continue to be undiagnosed, or diagnosed but treated with sub-standard
care. This allows transmission of TB in the community to continue,"
said Katherine Floyd, coordinator of TB monitoring and evaluation for
WHO's Stop TB Department. "Global targets set for 2015 - to halve
cases and deaths compared to 1990 levels - will not be achieved
without increased funding in the next four years."

 Floyd noted that the cancellation of Round 11 funding by the Global
Fund - which provides about $500 million for TB programmes globally
each year - could have severe repercussions.

 "In many countries, Global Fund investments represent 50 percent or
more of the total funding that is available. Cancellation of Round 11
means that some countries will lose the opportunity to apply for a new
stream of funding," she added. "More positively, much of the funding
from the Global Fund in the next three to four years was already
committed in earlier rounds - for HIV, TB and malaria combined there
is around $10 billion to disburse from previous rounds in 2012 and
2013.

 "What is really critical is that the available funding from previous
rounds is used for high-impact, cost-effective interventions."

 While all other regions are on track to achieve a 50 percent decline
in mortality by 2015, Africa is unlikely to achieve this target;
officials say poor funding is the main stumbling problem.

 Strengthening diagnostics

 The report highlights the need to strengthen diagnostics; of the 36
countries on the list of 22 high-burden TB countries and 27 high
multi-drug resistant TB (MDR-TB) burden countries, 20 have less than
the benchmark of one laboratory capable of performing culture and drug
susceptibility testing per five million people.

 Kenya is one of the better-funded programmes on the continent, with
both the government and international partners - including the US
government - contributing large amounts to diagnosis and treatment of
TB. However, Joseph Sitienei, head of Kenya's National TB and Leprosy
Control Programme, told IRIN/PlusNews the country faced a $16 million
gap to finance its activities in the coming year.

 "At the moment, we have 1,300 diagnostic sites for TB nationally, but
in order to effectively tackle the disease, we need many more; we need
at least 12 labs that are able to do TB culture, but nationally we
have only one. With more money, we would also be able to better
identify and treat people with drug-resistant strains of TB.

 "There is no shortcut; the government must allocate the resources," he said.

 Kenya is treating some 290 out of 320 identified cases of MDR-TB at a
cost of over $22,000 per patient, compared with about $78 for a course
of first-line drugs. It is estimated the country has more than 2,000
cases of MDR-TB.

 Sitienei noted that more funds for TB would also allow the government
to focus on treatment, paediatric TB and mitigating the impact of HIV
in TB patients.

 Research funding

 According to Floyd, gaps in funding for TB research and development
(R&D) are another concern. "Funding for R&D... actually fell between
2009 and 2010. Current funding is only one-third of the $1.8 billion
per year that is estimated to be needed in the Stop TB Partnership's
Global Plan to Stop TB 2011-2015," she said.

 A recent report [
http://www.treatmentactiongroup.org/sites/tagone.drupalgardens.com/files/TAG%20TB%20R%26D%202011%20Report.pdf
] by the policy think-tank, Treatment Action Group, found that 71
donors invested $617.1 million in TB R&D in 2010 - a 0.3 percent
decline from 2009 levels, but a 73 percent increase since 2005.

 WHO's report notes there are several promising new drugs in the
pipeline and nine vaccine candidates for the prevention of TB in Phase
I or Phase II. However, according to a 2011 study [
http://jid.oxfordjournals.org/content/204/suppl_4/S1187.full ]
published in the Journal of Infectious Diseases, the limitations of
existing TB diagnostic tools are significantly hampering tuberculosis
control efforts, particularly in areas with high HIV prevalence and
drug-resistant TB.

 "If the fight against TB [were] fully funded in the next four years
in line with the Stop TB Partnership's Global Plan to Stop TB
2011-2015, then TB mortality would be cut in half by 2015 compared
with its level in 1990; the number of cases would be falling globally
and in all major regions," said Floyd.

 "About 30 million people with TB would have been successfully treated
between 2011 and 2015 and there would be much better diagnosis and
treatment of MDR-TB and much better treatment for TB patients
co-infected with HIV."

 kr/mw

[END]

This report online: http://www.plusnews.org/report.aspx?reportID=94355



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