Big Pharma in Africa: Weighing corporate citizenship and the bottom
line – Adam Robert Green



April 29, 2013










Glaxo Smith Kline (GSK) is one of the biggest players in the
pharmaceuticals industry in Africa.

In the early 2000s, pharmaceutical companies were high on activists’
hit lists, prompted by Big Pharma’s ill-advised attempt to sue the
South African government for patent infringement on HIV drugs; an
attempt to deal with the country’s epidemic by allowing cheaper,
generic copies to be sold.

Today, the discourse seems merrier. Charities and NGOs sit down with
the same companies, discussing how best to confront public health
challenges in the developing world. The talk is of partnerships and
‘win-wins’. 0It isn’t all idle chatter. Drug donations, reinvestment
of profits in developing countries and a more flexible approach to
intellectual property have all signalled a more collaborative approach
from industry with the likes of GlaxoSmithKline, Sanofi, Johnson and
Johnson and Merck all performing well in the 2012 Access to Medicine
Initiative.

But while talk of a new era of friendship is appealing (not least to
the companies), there are still unresolved debates about the role that
companies play in shaping the public health agenda in developing
countries. Even the most seemingly charitable acts have come under
scrutiny.

Take drug donations. While giving people free medicine might seem a
sure-fire winner for corporate PR and the world’s poor, some
practitioners have reservations. Firstly, donations may focus the
public health community on interventions for which companies have
cures – albeit donated ones – without sufficient consideration of cost
effectiveness, opportunity cost or prioritisation. Such factors are
relevant, as free donations can lock governments and donors into
particular programmes which they later have to fund themselves.

One example is the HPV vaccination programme for cervical cancer in
Rwanda, enabled by a donation from Merck. After three years, the
freebies expire, but Merck promised to provide Rwanda with a
discounted access price to the vaccine. Assuming donors and
governments pick up the bill, the donations could be interpreted as
market-priming – creating the conditions for adoption – rather than
corporate citizenship.

This might not be a problem if it were a drug for TB, malaria or AIDS
– but critics of the HPV donation asked why cervical cancer received
such a comprehensive effort in Rwanda – reaching 95 percent for 11
year old girls -  when disease incidence lags well behind other
vaccine-preventable diseases in the developing world (see here for the
Rwandan health minister’s persuasive rebuttal).

Others point out that while Rwanda’s HPV coverage rates are laudable,
other basic interventions – from tackling diarrhoea or ensuring women
are provided with medical experts during childbirth – are  still
behind, raising questions about prioritisation.

As any public health official will tell you, there are no end of
worthwhile diseases to tackle. The plight of a health ministry is
making the difficult choices about what gets resources, and what does
not. Critics say there are no – or not enough – comprehensive
cost-effectiveness studies around donations. For cervical cancer, for
instance, screening and treatment were considered by some to be more
favourable options on a cost-effectiveness basis.

Some public health experts believe that ‘pull’ (incentives) mechanisms
might be a better way of bringing the private sector compared to
‘push’ measures likes donation programmes. One example is the Advanced
Market Commitment tool, where donors pledge to purchase developing
country disease-focused vaccines or medicines, giving companies a
commercial buyer and thus a reason to risk their R&D investment and
product development. The mechanism “removes uncertainty for donors,
governments, and vaccine manufacturers and improves availability and
access” says Peter Shelby, associate director of communications at the
International Federation of Pharmaceutical Manufacturers and
Associations.

GSK’s pneumococcal vaccine – introduced in Kenya’s national
immunisation programme in 2011 – benefited from AMC. But it was
already a late-stage product, and AMC has not yet been used again.
“Channelling such money should not be a problem from a [donor]
Ministry of Finance or Treasury point of view, because they are such
small amounts of money – you can’t imagine the US or UK couldn’t do
that when the time comes,” says Amanda Glassman at the Center for
Global Development in Washington.

But for companies to believe the money is real rather than a mere
pledge by aid ministers, it has to be locked away safely. In the
current climate of austerity, the idea of unused public money is not
appealing for Western taxpayers, notes Glassman. And some governments
– notably the US and Japan – have trouble participating in multi-year
commitments that represent a fiscal contingency.

No-one should expect Big Pharma to act as a charity – for one thing,
such behaviour will be superficial and unsustainable. The challenge is
to establish where ‘corporate citizenship’ stops and the bottom line
starts. As the recent intellectual property rights clash with Novartis
in India shows, the ‘people over profit’ debate has not yet been
dispensed with.

Adam Robert Green is senior reporter with This is Africa, a
publication from the Financial Times.

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