Thank you Eric, I just found out the Peak picking filter in msconvert will 
centroid the data. I guess the problem is solved!

thank you all!

SunSun

On Tuesday, March 3, 2015 at 11:56:00 PM UTC+8, Eric Deutsch wrote:
>
> ProteoWizard’s msconvert **can** convert profile to centroided. That it 
> didn’t for you means that either incorrect settings were applied or there 
> is some other glitch to be fixed.
>
>  
>
> *From:* spctools...@googlegroups.com <javascript:> [mailto:
> spctools...@googlegroups.com <javascript:>] *On Behalf Of *Frédéric 
> DELOLME
> *Sent:* Tuesday, March 03, 2015 3:12 AM
> *To:* spctools...@googlegroups.com <javascript:>
> *Subject:* Re: [spctools-discuss] how to convert profile data in RAW to 
> centroid data in mzXML?
>
>  
>
> Hi SunSun,
>
> Did you try to check the "Centroid all scans (MS1 and MS2) -- meaningful 
> only if data was acquired in profile mode" in the TPP Conversions options ?
>
> Fred
>
> Le 03/03/2015 11:34, zeyu sun a écrit :
>
> Hi,  
>
> I'm wondering if there is any tools can convert profile data in RAW to 
> centroid data in mzXML? I have tried ProteoWizard, but it didn't change 
> profile data to centroid data. I current don't have access to Xcailbur. 
>
>  
>
> thanks!
>
>  
>
> SunSun
>
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