Dear all I can't find a good place to completely understand RT-RTCAT options in peptide prophet. This is all that I've understood. Correct me if I am wrong:
RT model compares peptide's retention times with those learned using an ANN or a LR model. The learned retention times can be produced using RT Training tool in TPP GUI. The model will eventually reward or penalize hits by comparing their retention time with those from the model. Here are my questions: 1. Is this the algorithm of the ANN:* Improved Peptide Elution Time Prediction for Reversed-Phase Liquid Chromatography-MS by Incorporating Peptide Sequence Information : Konstantinos Petritis et al.* 2. Is there a paper where I can read exactly how RT model works? 3. Can I provide my own set of retention times for RT model instead of using RTCalc? 4. What is RTCAT? What is the catalog file? How does it look like? How can I create it? Thank you very much. Sincerely, Ali -- You received this message because you are subscribed to the Google Groups "spctools-discuss" group. To unsubscribe from this group and stop receiving emails from it, send an email to spctools-discuss+unsubscr...@googlegroups.com. To post to this group, send email to spctools-discuss@googlegroups.com. Visit this group at https://groups.google.com/group/spctools-discuss. For more options, visit https://groups.google.com/d/optout.
