20240417_AN_171_POS_LCMSMS_00.mzML
<https://drive.google.com/file/d/1qNf8C08bcg0KwF56HmonihILxh3uVqyU/view?usp=drive_web>
please find the mzml file shared through drive

On Wed, Jul 24, 2024 at 12:40 AM sudarshan kumar <[email protected]>
wrote:

> Thank you so much  David,
> Please find the screenshot of what I am getting.
> I am sharing the file also for you to check please.
> Best regards,
> Sud
>
>
> On Tue, Jul 23, 2024 at 10:16 AM David Shteynberg <
> [email protected]> wrote:
>
>> Hello Sudarshan,
>>
>> Although it is not possible to tell exactly what happened here without
>> more information, the usual suspects are:
>>
>> 1.  Data Quality
>> 2.  Incorrect Database
>> 3.  Incorrect Parameters
>>
>> I just ran a test of X!Tandem locally on the ISB18 dataset.  The search
>> ran and the TPP validation generated PSMs with positive probability
>> values.  If you are able to provide more information about your specific
>> analysis or post your dataset online for download I would be happy to take
>> a closer look.
>>
>> Cheers!
>> -David
>>
>>
>>
>>
>> On Jul 23, 2024, at 4:56 AM, sudarshan kumar <[email protected]>
>> wrote:
>>
>> Hi,
>> Can you please explain why?
>> When I searched with tandem, IT shows all good hits as I expected from
>> the sample.
>> But when I used peptide prophet, The result is all 0 probability?
>> I tried merging 4 files and individually also. But in all cases the
>> probability comes to 0.
>>
>> where is the problem>
>>
>> Best
>>
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>
>
> --
> -------------------------------------------------------------------
> The real voyage of discovery consists not in seeking new lands but seeing
> with new eyes. — Marcel Proust
>
> Dr. Sudarshan Kumar
> (Fulbright-Nehru Fellow)
> (B.V.Sc.& A.H., M.V.Sc., PhD.)
> Sr. Scientist
> Animal Biotechnology Center
> (Proteomics and Cell Biology Lab.)
> National Dairy Research Institute Karnal, 132001
> Haryana, India
> Contact No 09254912456
> URL www.ndri.res.in
> Orcid Id: https://orcid.org/0000-0002-9816-4307
>
>

-- 
-------------------------------------------------------------------
The real voyage of discovery consists not in seeking new lands but seeing
with new eyes. — Marcel Proust

Dr. Sudarshan Kumar
(Fulbright-Nehru Fellow)
(B.V.Sc.& A.H., M.V.Sc., PhD.)
Sr. Scientist
Animal Biotechnology Center
(Proteomics and Cell Biology Lab.)
National Dairy Research Institute Karnal, 132001
Haryana, India
Contact No 09254912456
URL www.ndri.res.in
Orcid Id: https://orcid.org/0000-0002-9816-4307

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