Hello James,
I agree to Pat that the easiest solution would be installing *xlrd* using 
*conda* or *pip*. Though whether you can use *conda* or *pip *is decided by 
whether you used the stand-alone installer for Spyder or installed it using 
Anaconda.

Kind regards
yfprojects

pa...@well.com schrieb am Mittwoch, 26. Mai 2021 um 18:46:59 UTC:

> Hi James - is there some reason you don't want to use either conda or 
> pip?  They'd resolve all the necessary dependencies.  Conda is the default 
> for Spyder but I found I was able to successfully switch Sypder to my 
> pre-existing Python 3.8 installation (under Tools | Preferences | Python 
> interpreter) and so I'm able to continue to use pip.
>
> Just now installed xlrd (which I'd used in the past) into my 3.8 
> installation - using pip - and had no problems.
>
> On Wednesday, May 26, 2021 at 9:36:36 AM UTC-7 jamesjoh...@gmail.com 
> wrote:
>
>>
>> Hello, all. I've been using Spyder to plot thermal data stored in an 
>> Excel file (.xlsx). I had a program using Pandas that would read the Excel 
>> file, put the data into numpy arrays, and then plot the data. The command I 
>> was using to read the excel file is 
>>
>> df = pd.read_excel(fname, sheet_name='Data')
>>
>> where fname is the .xlsx file name. This command worked fine with Spyder 
>> 3.x.x when I first downloaded it a while back, but since I updated to 5.0.3 
>> I started getting this error: 
>>
>> Missing optional dependency 'xlrd'. Install xlrd >= 1.0.0 for Excel 
>> support Use pip or conda to install xlrd.
>>
>> I tried changing the engine to openpyxl, but that returned this error: 
>>
>> Missing optional dependency 'openpyxl'.  Use pip or conda to install 
>> openpyxl. 
>>
>> I've looked at several tutorials and articles addressing this issue, but 
>> nothing has worked. I've also tried uninstalling and reinstalling Spyder 
>> with no luck. 
>>
>> Any assistance would be much appreciated. 
>>
>

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