[sqlite] How to set pragma page_size

[Ken]

 How does one set the page_size ?
 
 according to the documentation 
 "The page-size     may only be set if the database has not yet been created. "
 
 So how do you execute the pragma prior to creating the DB? without calling 
sqlite3_open to get a DB handle that is needed to call prepare/step ?
 
 Ive also tried setting this via -DSQLITE_DEFAULT_PAGE_SIZE=4096 at compile 
time and still get the default pagesize of 1024.
 
 Thanks