Probably you need to increase process limit

https://benohead.com/blog/2012/08/02/linux-check-the-open-files-limit-for-a-given-process/

This may be done via systemd unit file or drop-in

LimitNOFILE
https://www.freedesktop.org/software/systemd/man/systemd.exec.html

On Sun, Jul 25, 2021 at 9:44 AM 崔群 <[email protected]> wrote:
>
> Dear sir:
>        I have some problems。the kamailio version is 5.3.0. My linux version 
> is centos 7. the kamailio log:
> ERROR: <core> [core/tcp_main.c:3508]: send_fd_queue_run(): send_fd failed on 
> socket 63 , queue entry 1, retries 90, connection 0x7ff46e6b1b60, tcp socket 
> 218, errno=11 (Resource temporarily unavailable)
> ERROR: {1 12529 MESSAGE 359bf0410a7e471c950623e3f7a3b17b} <core> 
> [core/kemi.c:94]: sr_kemi_core_err(): 202->408
> CRITICAL: <core> [core/tcp_main.c:4218]: send2child(): tcp child 6, socket 
> 65: queue full, 291 requests queued (total handled 10665748)
>
> This problem does not happen every time。When the number of user registrations 
> increases significantly, errors will appear。I tried to set the parameter 
> tcp_children is adjusted to 8, it will not appear frequently, but when the 
> number of user registrations increases to about 5000, errors will still 
> appear. My kamailio.cfg global parameters are set as 
> follows:tls_max_connections=65536,tcp_max_connections=65536,open_max_files=65536。
> I hope you can reply to me,thanks.
>
>
>
>
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