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SCHOOL OF HISTORY AND PHILOSOPHY OF SCIENCE
AND THE
 Australasian Association for the History, Philosophy and Social Studies of 
Science (AAHPSSS)<https://aahpsss.net.au>
Held in conjunction with the Sydney Centre for the Foundations of Science
SEMESTER ONE
RESEARCH SEMINAR SERIES
MONDAY 26th April 2021

Rene Dubos, the Autochthonous Flora, and the Prehistory of the Microbiome

PRESENTED BY: Nicolas Rasmussen, MPhil, PhD, MPH; FAHA, FAAAS
Professor Emeritus, School of Humanities & Languages
University of NSW

ABSTRACT: Only recently characterised by high-throughput sequencing methods 
that enable the study of microbes without lab culture, the human ‘microbiome’ 
(the microbial flora of the gut and various other parts of the body) is said to 
have revolutionary implications for biology and medicine. We must now 
understand ourselves as ‘holobionts’ like lichen or coral, multispecies 
super-organisms that consist of animal and symbiotic microbes in symbiotic 
combination, because normal physiological function depends on them.   In this 
talk I look at the 1960s research of biologist Rene Dubos, a forerunner figure 
mentioned in some historical accounts of the microbiome, and argue that he 
advanced the super-organism concept 40 years before the Human Microbiome 
Project was conceived.  Furthermore, scientist contemporaries valued this 
research and understood his views.  This raises the questions of why the 
concept was not welcomed as revolutionary at the time and why Dubos is not 
remembered for this contribution.

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WHEN:   MONDAY 26TH APRIL 2021
START:   FROM 5.00PM
ZOOM OPTION: https://uni-sydney.zoom.us/j/89869022658
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Unit for History and Philosophy of Science · University of Sydney · Sydney, NSW 
2006 · Australia

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