Comment by asmeurer:
PyPy support is coming (see issue 1026). Unfortunately, SymPy generally
runs at least as fast, if not slower on PyPy. You can try it yourself if
you don't believe me (I've only played with it minimally, so maybe some
things really are faster). The problem is that the JIT optimizations are
not so great with a lot of the object oriented stuff that SymPy uses
heavily, like metaclasses.
By the way, the content of this page is outdated, especially a lot of the
speed stuff.
You also might look at the Google Summer of Code project we had this year
relating to mechanics
(https://github.com/sympy/sympy/wiki/GSoC-2011-Report-Gilbert-Gede:-PyDy).
It hasn't all been merged yet, but it should be in by the next release.
For more information:
http://code.google.com/p/sympy/wiki/Motivation
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