There are different ways to organize this, but here is a compact way -- not
necessarily the best. I don't know what your 'func's look like so I am just
showing the transformation of nc by multiplying or dividing by 2:

def mul_xform(func):
    def product_bases(nc):
        if len(nc) == 2 or len(nc) == 1 and nc[0].is_Pow and nc[0].exp == 2:
            return Mul._from_args(nc)
        assert not nc
    def updater(p, func, m):
        if p.is_Mul:
          c, nc = p.args_cnc(split_1=False)
          if nc:
            nc = product_bases(nc)
            if nc not in m:
              m[nc] = func(nc)
            c = Mul._from_args(c)
            return c*m[nc]
        return p
    return Transform(lambda k: updater(k, func, {}), lambda w: w.is_Mul)

T2 = mul_xform(lambda x: 2*x)
Thalf = mul_xform(lambda x: x/2)

>>> var('ex ey', commutative=False)
(ex, ey)
>>> (15*ex**2 + 6*ey*ex + ex).xreplace(T2)
ex + 30*ex**2 + 12*ey*ex
>>> _.xreplace(Thalf)
ex + 15*ex**2 + 6*ey*ex

/c

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