Pranam

EXPIRY DATE OF MEDICINES ETC

1     There is so much wastage of drugs as they are not used in time.
Medications are expensive, and in the Asian and African continents, where
many have the problem of affordability the debate is to see if the
medication could be used even after the expiry date without losing the
efficacy. Most of drug expiration dates information is from the study
conducted by the Food and Drug Administration at the request of the
military. With a large and expensive stockpile of drugs, the military faced
tossing out and replacing its drugs every few years. What they found from
the study is that 90% of more than 100 drugs, both prescription and
over-the-counter, were perfectly good to use even 15 years after the
expiration date. Hence, the expiration date doesn't really indicate a point
at which the medication is no longer effective or has become unsafe to use.

2     The expiration date is the final day that the manufacturer guarantees
the full potency and safety of a medication. Drug expiration dates exist on
most medication labels, including prescription, over-the-counter (OTC) and
dietary (herbal) supplements. Proper storage of medications may help to
extend their potency. The bathroom and medicine cabinet are not ideal
places to store medications due to heat and humidity. Similarly,
medications should not be left in a hot car. Medications remain most stable
in dry, cool spaces away from light. Keep the prescription bottle caps
tightly closed and always keep medications out of reach of children and
pets.

3   The 2015 commentary in Mayo Clinic Proceedings, “Extending Shelf Life
Just Makes Sense,” suggested that drug makers could be required to set a
preliminary expiration date and then update it after long-term testing. An
independent organization could also do testing similar to that done by the
FDA extension program or data from the extension program could be applied
to properly stored medications  The United States' Center for Drug
Evaluation and Research officially recommends that drugs past their
expiration date be disposed of. It has been argued that this practice is
wasteful, since consumers and medical facilities are encouraged to purchase
fresh medication to replace their expired products, also resulting in
additional profits for pharmaceutical firms. According to the Food and Drug
Administration (FDA) study gets to the heart of medicine expiration and
safety. Updated: August 13, 2017, it turns out that the expiration date on
a drug does stand for something, but probably not what you think it does.
Since a law was passed in 1979, drug manufacturers are required to stamp an
expiration date on their products. This is the date at which the
manufacturer can still guarantee the full potency and safety of the drug.

4     Medical authorities state that expired medicine is safe to take, even
those that expired years ago. It's true the effectiveness of a drug may
decrease over time, but much of the original potency still remains even a
decade after the expiration date. Excluding nitroglycerin, insulin, and
liquid antibiotics, most medications are as long-lasting as the ones tested
by the military. Placing a medication in a cool place, such as a
refrigerator, will help a drug remain potent for many years. Solid dosage
forms, such as tablets and capsules, appear to be most stable past their
expiration date. Drugs that exist in solution or as a reconstituted
suspension, and that require refrigeration (such as amoxicillin
suspension), may not have the required potency if used when outdated. Loss
of potency can be a major health concern, especially when treating an
infection with an antibiotic. In addition, antibiotic resistance may occur
with sub-potent medications. Drugs that exist in solution, especially
injectable drugs, should be discarded if the product forms a precipitate or
looks cloudy or discolored.

5     A study by Khanchandani on efficacy, safety concern and disposal
practices followed for expired drug preparations among medical personnel,
found that 89.39% had knowledge that expiry date depends on both
manufacturing and storing condition. Ninety one percent of subjects
responded correctly that the drug should be best stored in cool dry and
dark places. During the study they found out that the majority consider
expired drug use is not safe but 89.39% of subjects were aware about not
using insulin, liquid antibiotic, nitroglycerin after expiry. The testing
conducted by the US FDA ultimately covered more than 100 drugs prescription
and OTC drugs. The result showed that about 90% were safe and effective as
long as 15 years past their original expiration date. Loel Dawis,
expiration date chief said that with a handful of exceptions notably
nitroglycerin, Insulin and Liquid antibiotic most drugs are probably as
durable as the agency tested.

6  Potency and efficacy      Medication's potency gradually decreases
starting from the moment of its manufacture. This process is not in any way
spontaneous after the expiry date. Expired drugs have not necessarily lost
their potency and efficacy. The expiration date is only an assurance that
the labeled potency will last at least until that date. Ongoing research
shows that stored under optimal conditions, many drugs retain 90% of their
potency for at least five years after the labeled expiration date, and
sometimes longer. Even 10 years after the expiration date many
pharmaceuticals retain a significant amount of their original potency.
Solid dosage forms, such as tablets and capsules, are most stable past
their expiration date. Drugs that exist in solution or as a reconstituted
suspension may not have the required potency if used when outdated.

7     The best evidence of acceptable potency of the medications beyond
their expiration date is provided by the Shelf Life Extension Program
(SLEP) undertaken by the FDA for the Department of Defense. The aim of the
SLEP program was to reduce medication costs for the military. SLEP has
found that 88% of 122 different drugs stored under ideal conditions should
have their expiration dates extended more than 1 year, with an average
extension of 66 months, and a maximum extension of 278 months.  Certain
medications have a narrow therapeutic index and little decreases in the
pharmacological activity can result in serious consequences for patients.
Monoclonal antibodies should be included in this group. These drugs should
not be used beyond the expiry date.
8   Hence marketing strategy is the root of expiration. And Ayurvedic is
FLORA AND FAUNA and where is expiry for nature?  KR  IRS  19722

On Mon, 18 Jul 2022 at 19:14, 'gopala krishnan' via iyer123 <
[email protected]> wrote:

> QUES ANSW MEDICAL  07-2022-14
>
> Dear friends,
>
> These are information compiled as QA by me in 1998’s-2014’s and stored in
> my computer. They are posted by *very  learnt doctors in kidshealth.org
> <http://kidshealth.org> etc. *
>
> *Many improvements have come in medical field.  Hence some information may
> have additions or some times changes.*
>
> *These are for general information, and for  any health  problem one has
> to  consult doctor.*
>
> *BEING COMPILATION THERE MAY BE  ERRORS.*
>
> Sincerely,
>
> *R. Gopalakrishnan, 78, dated 18-07-2022*
>
> Q1. Do Tulsi products have curing effects?
>
> A1Yes. Ayurvedic tulsi preparations have significantly reduced the
> symptoms of viral hepatitis.
>
> In diabetics it helps in lowering the blood sugar level. It raises the
> human body immunity by increasing the antibody production.
>
> My note- I am told Tulsi theerth increases longevity and hence given in
> temples
>
> Q2 From where we have the maximum dust of the house?
>
> A2   Most dust particles in your house are made from dead skin.
>
> Q3 What is the name for milk in Ayurveda? How many types of milks are
> described in Ayur veda?
>
> A3  Milk is called amrut in Ayurvedic texts. Ayurveda describes the
> properties of eight kinds of milk: the milk of cows, buffaloes, goats,
> sheep, *camels, elephants, horses and women. While cows milk is used as
> food, other kinds of milk are used as medicine.*
>
> Q4 What are the Health benefits of milk?
>
> A4 Milk is sweet in taste and has a sweet after-digestion effect. It is
> unctuous, lubricant and cold by nature. It increases strength and vitality. 
> *It
> is a good brain tonic that helps enhance memory and the grasping capacity
> of a child when consumed daily.*
>
> Milk is rich in proteins, fats, carbohydrates, vitamins and minerals.
> Being rich in calcium, it helps heal fractured bones. *When consumed in
> old age, it strengthens bones. When consumed during pregnancy,  milk gives
> strength to the pelvic bones and helps increase milk secretion in case of
> lactating mothers. *
>
> Q5  What are the Medicinal properties of specific types of milk?
>
> A5  Buffalo milk is heavy to digest. It should be consumed by those who
> want to get rid of their frequent appetite and those suffering from
> insomnia.
>
> Goat milk is light. It helps those suffering from asthma, fever and
> diarrhoea.
>
> Sheep milk does not taste good but helps reduce the complaints caused by
> vata dosha in the body.
>
>  Camel milk reduces flatulence, oedema, ascitis, piles.
>
> Human milk helps treat eye infections. In the case of infants it is used
> as eye-drops. It helps alleviate certain disorders like ascitis.
>
> Pay attention to hygiene. Avoid fresh milk if you do not have good
> digestion. For easy digestion, boil milk and consume hot. But bear in
> mind that milk boiled frequently becomes heavy to digest.
>
> Q6 People with Phobia is not uncommon. What's a Phobia?
>
> A6  A  *phobia* is the fancy name for a fear. But a phobia isn't just any
> kind of fear.  A phobia is different because it is an extremely strong
> fear of a situation or thing. It is also a kind of fear that doesn't go
> away .
>
> A person who has a phobia will be afraid of something every time he or she
> sees or experiences it. She won't just be afraid once or twice. Person who
> have phobias often go out of their way to avoid the situation or thing that
> scares them.
>
> Claustrophobia is the fear of being in an enclosed space, like an
> elevator, a tunnel, or an airplane.
>
> Arachnophobia is a fear of spiders, whereas ablutophobia is a fear of
> washing yourself or taking a bath or shower.
>
> Q7 Why there are expiry dates for allopathic medicines and no expiry dates
> for Ayurvedic medicines?
>
> A7 There is no expiry date for ayurvedic medicines. Because there is no
> chemical in it.
>
> However it is told by doctors we need not throw away  the next day of
> expiry the allopathic medines. It can be used for one or two months more.As
> the expiry date approach the effect of chemicals also reduce.
>
> Similarly it has been observed though there is no expiry date as day go on
> the effect reduces notably.eg:Amirtangen
>
> Q8 What is sukraneethi about taking food by a king  after testing of
> poisoning?
>
> A8  The mere sight of the poisoned food makes a swan (Hansa) to totter,
> the black bee begins to make a noise, the peacock begins to dance, the
> cock begins to 'crow', the Heron (KRAUNCH PAKSHI) gets intoxicated, the
> monkey begins to pass 'filth' and urine, the mongoose (BABHRU) gets
> excited, the 'starling' (SAARIKA PAKSHI) starts vomiting- These are the
> ways to examine the poisoned food.
>
>  The king and his administrators must examine the food, whether it is
> poisoned or not, before consuming it
>
>
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