Do any of you know the mechanism by which caffeine causes vasoconstriction of
blood vessels to the brain, while elsewhere it triggers vasodilation? I think
the vasodilation may occur because methylxanthines like caffeine increase the
release of nitric oxide, which in turn relaxes smooth muscle, but what's
different in the CNS?

Linda Walsh
University of Northern Iowa
Cedar Falls, IA
[EMAIL PROTECTED]

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