What do you make of the finding that enteric coated aspirin may not be as effective as the uncoated variety.Something about enteric taking longer to release its ingredients. I could see this as an artifact in medical testing and the importance of considering "interaction" of variables before being conclusive of results. michael ----- Original Message -----i From: Wuensch, Karl L To: Teaching in the Psychological Sciences (TIPS) Sent: Tuesday, January 15, 2013 3:43 PM Subject: [tips] Physicians Aspirin Study
That study is great for illustrating how deceptive percentage of
variance explained statistics can be. They terminated this study prematurely
because the early returns showed an effect so large (odds ratio of about 1.8)
that it was deemed unethical to continue the study. In terms of variance
explained, the treatment accounted for about one tenth of one percent of the
variance in MI.
Cheers,
From: John Kulig [mailto:ku...@mail.plymouth.edu]
Sent: Tuesday, January 15, 2013 3:39 PM
To: Teaching in the Psychological Sciences (TIPS)
Subject: Re: [tips] Flu vaccine and p.6 level of significance
Nice replies (Jim C, Karl W and Mike P and others ..) so I won't repeat what
has been said except to note - as a tangent to the original posts - that in
some of my classes I spend time with the "relative risk" Karl W discusses. I
use the example of aspirin and MI (heart attack) in the 1988 (New England
Journal of Med?? if I remember) article of 22,000+ physicians who took aspirin
vs. placebo. My chi square calculated on their frequencies reveal p < .01, yet
the risk of MI only drops from 1.7% to .9% in the sample over the years
studied. As an absolute value, the % decrease is very small, but expressed as
relative risk we can say we cut the risk in half. Of course, any "significant"
decrease will be championed as the stakes are very high with MI .. and
sometimes high with flu as well ..
At any rate, I got MY flu shot! So I am OK. p < .05 :-)
==========================
John W. Kulig, Ph.D.
Professor of Psychology
Coordinator, University Honors
Plymouth State University
Plymouth NH 03264
==========================
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