I encountered this same issue in a freshly installed Ubuntu 18.04
system.

$ uname -a
Linux Machine 5.0.0-25-generic #26~18.04.1-Ubuntu SMP Thu Aug 1 13:51:02 UTC 
2019 x86_64 x86_64 x86_64 GNU/Linux

$ lsb_release -rd
Description:    Ubuntu 18.04.3 LTS
Release:        18.04

$ gnome-shell --version
GNOME Shell 3.28.4

To discover the error, I ran this app via command line:
$ /usr/bin/python3 /usr/bin/software-properties-gtk
ERROR:root:Authentication canceled, changes have not been saved
ERROR:root:Authentication canceled, changes have not been saved
ERROR:root:Authentication canceled, changes have not been saved
ERROR:root:Authentication canceled, changes have not been saved
ERROR:root:Authentication canceled, changes have not been saved
ERROR:root:Authentication canceled, changes have not been saved

The above errors appear every time the mouse arrow left-clicks on the
checkbox.

I circumvent this issue by:
1. left-click on Canonical Partners to select it.
2. left click on the edit button.
3. after the Edit Source GUI appeared, I left-clicked on the "OK" button.
4. finally when I left-click on the checkbox of Canonical Partners, the 
checkbox becomes selected.

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You received this bug notification because you are a member of Ubuntu
Touch seeded packages, which is subscribed to software-properties in
Ubuntu.
https://bugs.launchpad.net/bugs/1727908

Title:
  Software & Updates application does not permit changes on the "Other
  Software" tab

Status in gnome-shell package in Ubuntu:
  Confirmed
Status in software-properties package in Ubuntu:
  Confirmed

Bug description:
  
  On the "Other Software" tab, I am unable to select "Canonical Partners".
  Similarly, the other checkboxes on the "Other Software" can not be clicked.
  Clicking on a checkbox has no effect, and a dialog requesting the admin 
password is not presented.

  However, activating or deactivating checkboxes on other tabs causes an
  authorization dialog to be presented to the user.

  I experience this bug in an an Xorg session.

  sources.list and sources.list.d have the following permissions:
  -rw-r--r--   1 root root  2897 Oct 26 22:35 sources.list
  drwxr-xr-x   2 root root  4096 Oct 26 21:29 sources.list.d

  All files in sources.list.d have the following permissions as this example:
  -rw-r--r-- 1 root root  189 Oct 25 21:50 google-chrome.list

  $ lsb_release -rd
  Description:  Ubuntu 17.10
  Release:      17.10

  $ apt-cache policy software-properties-gtk
  software-properties-gtk:
    Installed: 0.96.24.17
    Candidate: 0.96.24.17
    Version table:
   *** 0.96.24.17 500
          500 http://us.archive.ubuntu.com/ubuntu artful/main amd64 Packages
          500 http://us.archive.ubuntu.com/ubuntu artful/main i386 Packages
          100 /var/lib/dpkg/status

  ProblemType: Bug
  DistroRelease: Ubuntu 17.10
  Package: software-properties-gtk 0.96.24.17
  ProcVersionSignature: Ubuntu 4.13.0-16.19-generic 4.13.4
  Uname: Linux 4.13.0-16-generic x86_64
  NonfreeKernelModules: wl nvidia_uvm nvidia_drm nvidia_modeset nvidia
  ApportVersion: 2.20.7-0ubuntu3.1
  Architecture: amd64
  CurrentDesktop: GNOME
  Date: Thu Oct 26 22:45:09 2017
  InstallationDate: Installed on 2017-10-26 (1 days ago)
  InstallationMedia: Ubuntu 17.10.0 2017.10.25 amd64 "Custom Artful Aardvark"
  PackageArchitecture: all
  ProcEnviron:
   TERM=xterm-256color
   PATH=(custom, no user)
   XDG_RUNTIME_DIR=<set>
   LANG=en_US.UTF-8
   SHELL=/bin/bash
  SourcePackage: software-properties
  UpgradeStatus: No upgrade log present (probably fresh install)

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