ReTux uses the SGE Game Engine:

http://stellarengine.nongnu.org

And xSGE:

http://xsge.nongnu.org

The SGE currently uses Pygame, but I'm intending to develop a new implementation that can work with PyPy (probably PySDL2 or Pyglet-based) when the SGE reaches version 1.0. (I intend for that to happen after reTux is finished.)

A SGE implementation optimized with Cython is in fact another possibility I've considered. An implementation in pure-python also has the possible benefit of greater portability, though, so that takes priority. :)

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