I just ran the following test using my current source tree for python-twitter and got no errors. You may want to use debugHTTP=True to look at what the POST being sent to Twitter is.
import twitter api = twitter.Api(consumer_key='####', consumer_secret='####', access_token_key='####', access_token_secret='####', debugHTTP=True) print api.VerifyCredentials() -- Twitter developer documentation and resources: http://dev.twitter.com/doc API updates via Twitter: http://twitter.com/twitterapi Issues/Enhancements Tracker: http://code.google.com/p/twitter-api/issues/list Change your membership to this group: http://groups.google.com/group/twitter-development-talk