The Society for Risk Analysis, the Electric Power Research Institute, Resources for the Future, and the U.S. Environmental Protection Agency will present the following workshop,. ADVANCED METHODS FOR DOSE-RESPONSE ASSESSMENT: BAYESIAN APPROACHES On September 18-20, 2000, at the Conference Center of Resources for the Future, 1616 P Street, NW, Washington, DC 20036 Make plans now to join us for this informative event. Seating is limited, so please register early. Reduced fee registrations are available until 8/14/00. Visit the Society for Risk Analysis web site at www.sra.org and download a pdf file with registration information. To link directly to the announcement, click on http://www.sra.org/events.htm#workshop This three-day workshop is intended to identify methods to satisfy an unmet need in human health risk assessment, estimating responses at low doses. Most current assessments use some kind of upper bound on response. Such estimates are useful for many purposes, but sometimes an unbiased estimate is needed. The organizers (primarily James D. Wilson of Resources for the Future and Annie Jarabek of the U.S. Environmental Protection Agency) suggest that approaches based on Bayesian logic may lead to low-dose estimates of response and offer the workshop to explore this possibility. The workshop will begin with an introduction to Bayesian analysis, for persons unfamiliar with the methods, and will cover applications of Bayesian methods in medical research, space exploration, exposure assessment, and ecological risk. The workshop will explore the use of Bayesian methods in modeling dose-response relationships and integrating disparate data in dose-response estimation. It will conclude with discussion of future directions and research needs. Some of the invited speakers and their proposed topics are: William Farland; U.S. Environmental Protection Agency - Purpose and Importance of the Workshop. Thomas Louis; University of Minnesota - Theory of Bayesian Logic and Statistics � Introduce Concepts, Illustrate Range of Uses, Describe Limitations. Kevin Brand; University of Ottawa - Using Readily-Available Software to Compute Posteriors, Given Appropriate Input. D. Warner North; Northworks - Applying Bayesian Logic in a Decision Context � Review Theory; Describe Application to Relevant Decisions. Donald Berry; M.D. Anderson Cancer Center - Use of Bayesian Approaches in Medical Research � Clinical Trials � Illustrate Use, Need to Identify Appropriate Priors. Alison Cullen; University of Washington - Identifying Inputs. Mitchell Small; Carnegie-Mellon University - Using Dispararate Data in Exposure Assessment. Igor Linkoff; Menzie-Cura Associates - Application to Ecological Risk . Illustrate Use, Illustrate How to Deal With Errors in Data. L. Anthony Cox; Cox Associates - Bayesian Risk Assessment: Combining Evidence from Multiple Sources. Daniel Byrd; CTRAPS - Constructing an Exposure-Response Function. R. Wyzga; Electric Power Research Institute - Issues in Estimating Dose-response Functions. Annie Jarabek; US Environmental Protection Agency and Vic Hasselblad; Duke University - Using a Bayesian Approach to Integrate Data. Donald Barnes; U.S. Environmental Protection Agency - Where Do We Go >From Here? Applications and Research Needs. --- Daniel M. Byrd III, Ph.D., D.A.B.T. President, Consultants in Toxicology, Risk Assessment and Product Safety Suite N707 560 N Street, SW Washington, DC 20024 (202)484-7707 - phone (202)484-0616 - fax [EMAIL PROTECTED] - email
