Within an European H2020 project the Koeppl Lab at the Department of Electrical 
Engineering and Information Technology of Technische Universität Darmstadt, 
Germany invites applications for a

PhD position – Machine Learning & Causal Inference,

initially limited for 3 years.

The multi-partner project is concerned with the assembly of high-quality 
medical and molecular data on paediatric cancers in order to perform 
ML/AI-based predictions on patient outcome and drug efficacy. The Koeppl lab 
has the lead in this project for the development of algorithms for the 
reconstruction of molecular interaction networks from high-throughput 
multi-omics data. Emphasis will be placed on probabilistic graphical models and 
their use in causal inference. Moreover methods for the inference in larger, 
relational networks comprising cell-type information, patient and drug data 
should be developed. This will provide the formal basis of the virtual patient 
modelling efforts in the consortium.

The PhD student will work on mathematical analysis and method development with 
the particular focus on utilizing recent high-dimensional single-cell data. 
Moreover, the student will work on algorithms for the incorporation and mining 
of structured and unstructured data related to cancer biology into a relational 
graph.

Opportunity for further qualification (doctoral dissertation) is given. The 
fulfillment of the duties likewise enables the scientific qualifications of the 
candidate.
The Technische Universität Darmstadt provides the environment and support for 
publishing and presenting original research results at leading international 
conferences and in scientific journals.

Your profile:
• M.Sc. in Statistics, Mathematics, Computer Science, Electrical Engineering or 
Physics
• ideally, experience in the domain of bioinformatics, especially analysis of 
high-throughput data
• appreciation for interdisciplinary work and proactive drive to collaborate in 
a team

Application:
Your application must include a cover letter explaining succinctly why you are 
interested in this position and why you believe you are the right candidate a 
list of passed courses and obtained grades a CV contact details of at least two 
references (academic advisors) of yours.
The Technische Universität Darmstadt intends to increase the number of female 
employees and encourages female candidates to apply. In case of equal 
qualifications applicants with a degree of disability of at least 50 or equal 
will be given preference. Wages and salaries are according to the collective 
agreements on salary scales, which apply to the Technische Universität 
Darmstadt (TV-TU Darmstadt). Part-time employment is generally possible.

Please send your application, incl. the above mentioned documents, as one 
single PDF file to: 
off...@bcs.tu-darmstadt.de<mailto:off...@bcs.tu-darmstadt.de> indicating the 
application code number within the subject line. Incomplete applications and 
applications in different file formats will be discarded.

Code No. 483
Application deadline: February 28, 2021



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