I have mouse M505 (almost same) but for this bug I think it is the software related to the Unifying dongle which has problem.
This is a regression because I never had such trouble with previous ubuntu release. $ lsusb Bus 002 Device 002: ID 046d:c52b Logitech, Inc. Unifying Receiver $ xinput --list --short ⎡ Virtual core pointer id=2 [master pointer (3)] ⎜ ↳ Virtual core XTEST pointer id=4 [slave pointer (2)] ⎜ ↳ SynPS/2 Synaptics TouchPad id=10 [slave pointer (2)] ⎜ ↳ TPPS/2 IBM TrackPoint id=11 [slave pointer (2)] ⎜ ↳ Logitech Unifying Device. Wireless PID:101d id=12 [slave pointer (2)] I tried few things (compare lsmod result before/after unplug/plub the mouse) => same for usbhid module in /etc/modules => no effect do $ sudo rmmod hid_logitech_dj $ sudo modprobe hid_logitech_dj is enough to restore the mouse (at each boot!!!) In attachment see my kern.log. I noticed that mouse is not detected during boot, but only when I unload/re-load the module. ** Attachment added: "/var/log/kern.log (full)" https://bugs.launchpad.net/ubuntu/+source/xorg/+bug/975843/+attachment/3122514/+files/kern.log -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/975843 Title: Logitech Mouse M510 don´t work each second boot To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/xorg/+bug/975843/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs