Is it possible your system has booted into a read-only file-system mode?  (I've 
already reported that bug, and Mozilla won't respond either, presumably  since 
it can't write any session or cache files )
Is it consistent upon multiple reboots? (mine is only intermittent, usually it 
boots ok) 
Are you able to open a terminal window via ctrl-alt-T?  In a terminal, do you 
get error msgs about locked files or other access problems? (For example, 
running 'sudo apt-get update?
What do you get with
Have you run 'sudo apt-get install -f" ? (fix packages)
What file permissions on your home dir do see when you run 'ls -l /home' ?

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https://bugs.launchpad.net/bugs/994778

Title:
  after upgrading to 12.04, unable to use any application

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