I incurred in this same bug after installing the proposed HWE kernel (that AFAIK is expected to be released with the incoming 16.04.2 LTS point release) in my Xenial machine.
I installed the 4.8.0-32.34~16.04.1 kernel (from the proposed channel) today, after reading the request for testing that Leann Ogasawara posted one month ago to the Ubuntu Announce list. However, after I executed "sudo apt-get install linux-generic- hwe-16.04-edge", Apport catched a DKMS problem that it recognized as a duplicate of this bug. I think VirtualBox should work out-of-the-box with the HWE kernel. ** Attachment added: "DKMS error log" https://bugs.launchpad.net/ubuntu/+source/virtualbox/+bug/1629870/+attachment/4799171/+files/make.log -- You received this bug notification because you are a member of Ubuntu Bugs, which is subscribed to Ubuntu. https://bugs.launchpad.net/bugs/1629870 Title: Trouble installing mainline kernel 4.8: virtualbox-dkms 5.0.24-dfsg- 0ubuntu1.16.04.1: virtualbox kernel module failed to build To manage notifications about this bug go to: https://bugs.launchpad.net/ubuntu/+source/virtualbox/+bug/1629870/+subscriptions -- ubuntu-bugs mailing list ubuntu-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/ubuntu-bugs