answer #2 worked for me. could start synaptic again on Ubuntu 17.10

Intel® Core™ i5-6500 CPU @ 3.20GHz × 4 
Intel® HD Graphics 530 (Skylake GT2)
3.26.2
64-bit

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https://bugs.launchpad.net/bugs/1712089

Title:
  Invalid MIT-MAGIC-COOKIE-1 keyUnable to init server: Could not
  connect: Connection refused

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